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Hydrochlorothiazide / losartan User Reviews & Ratings

Brand names: Hyzaar

Hydrochlorothiazide / losartan has an average rating of 6.4 out of 10 from a total of 60 reviews on Drugs.com. 57% of reviewers reported a positive experience, while 30% reported a negative experience.

Condition Avg. Rating Reviews Compare
High Blood Pressure  
6.4
60 reviews for High Blood Pressure 273 medications
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Reviews for Hydrochlorothiazide / losartan

  • katey...
  • Taken for less than 1 month
  • August 15, 2019

For High Blood Pressure "Sure..it has lowered my BP but at a cost. I have gained 7 lbs in 2 weeks, short of breath, only want carbs, constantly hungry and thirsty. If I am not constantly eating I am shaking indicating low blood sugar. I am not lazy. I do strength training as well as cardio at LEAST 3 x's/wk and up until taking hydrochlorothiazide with losartan I could watch my diet as well as had the metabolism of a person much younger than I. I hate this drug..demanding something better if I have to go completely natural. Horrid drug, horrid past..nope."

3 / 10
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57 Report
  • dad
  • February 15, 2014

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I've been on for a week. I've never felt better, I've had an on and off fast heart beat and arrhythmia for 15 years, been checked multiple times for by heart doctor, always came back negative. I haven't felt this good since I was a kid, no more fast heart beat, no more chest pain or tightness, I feel relaxed and normal, a little thirsty but that's it."

10 / 10
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87 Report
  • Hawkeye...
  • December 20, 2014

For High Blood Pressure "I was on lisinopril, but after a few weeks I developed the dreaded cough side effect. It took me over a month and a half to get rid of it. My dr. switched me to losartan. So far it has worked great. No side effects other than drowsiness, but that's okay with me. I take it at night and it helps me sleeps. Helps with my blood pressure and insomnia, kills two birds with one stone. Most of all I'm just happy to get rid of that lisinopril cough. That was making my life miserable."

9 / 10
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77 Report
  • lovek...
  • January 9, 2008

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I have taking Hyzaar for 6 years without any side effects, my prescription co, wanted me to change to a different medication, they said there is not a generic, but thanks to drugs.com I found out there is a generic , Thank you for all the help when we need it."

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115 Report
  • Dress...
  • March 27, 2012

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "While it is effective in lowering blood pressure, I have experienced side effects, to include ringing in the ears, dizziness, rapid heart beat, odd muscle pain and slightly elevated liver values. I also experienced rapid weight gain when switched to a generic version of the medicine."

2 / 10
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90 Report

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  • geege...
  • Taken for 5 to 10 years
  • January 17, 2013

For High Blood Pressure "Nothing works better for me. I ran out and couldn't get a refill because I moved out of state. I tried lisinopril 20mg and it did not hold my pressure down. After monitoring it myself with a reading of 202/110 I ended up in the ER, why I didn't have a headache I don't know. I am now back on losartan/hydrochlorothiazide 100/25."

10 / 10
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76 Report
  • Texas...
  • January 19, 2016

For High Blood Pressure "For those who are having terrible leg cramps on BP medication. I had the same horrible problem to the point I was screaming my head off at times and could not walk. It was the HCTZ DIURETIC portion of my bp med that was causing it. NOT the Losartan part. This will be the same for any BP med that is blended with a HCTZ diuretic because Triamterene did the same thing. Since I don't really have any medical need for the diuretic, my doctor simply wrote me a script for the Losartan without the diuretic in it. Voila!! no more leg cramps! and my bp is still under control."

6 / 10
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59 Report
  • tiger
  • July 30, 2009

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I have had uncontrollable high blood pressure and hypothyroidism for over 15 years. All the different blood pressure medications the doctors have given me never came close to how well Hyzaar works. Not only has my blood pressure been lowered to near-normal (used to run 190 /120 ) but I have also lost over 25 pounds of fluid from the hydrochlorothiazide. Nothing but high marks for Hyzaar. No bad side effects. I feel the best I have felt in a long, long time!"

10 / 10
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90 Report
  • Hibo
  • February 26, 2017

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I have been using this medication for almost 12 years (50/12.5), my blood pressure was ok and most of the periodical blood analysis I made were ok, never had a noticeable side effects. For almost 10 days now, my BP is 150/100 and is not decreasing although I am taking the medicine. The work doctor said that my body might have adapted to the medicine, so I am seeing a specialist today to see what to do.."

8 / 10
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51 Report
  • Upset...
  • Taken for 1 to 6 months
  • December 14, 2015

For High Blood Pressure "I took the lowest dose of lisinopril available for 3 yrs before developing the dreaded cough. My Dr switched me to losartan 4 mos ago, again the lowest dose. After one month I started having intense leg cramps. When the bad cramps began affecting my rib cage if I just turned awkwardly, and the horrendous leg cramps kept me from sleeping, I quit taking the losartan (9 days ago). Within 48 hrs all these symptoms completely disappeared. I googled & found others had had the same problem. I'm 55 and felt worse than my 81 yr old dad. Now I feel 55 again! I'll see my Dr next week but I'm worried about any BP med now."

1 / 10
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56 Report
  • Shimmy
  • April 9, 2012

For High Blood Pressure "I started using Lisinopril HCTZ and had muscle ache, lower desire for sex, but the blood pressure was in control 110/80. After reporting to my doctor he suggested Diovan HCTZ, I started losing a lot of hair but sex drive got much better. Met the DR again and was concerned about my hair loss as I read about majority of Diovan users lost hair. Switched to Losartan HCTZ 50/12.5mg and the blood pressure was under control and the best since started taking blood pressure medication. In the morning is the best time to measure it, prior to taking the pill, as its 24 hours after taking the pill. This pill is the most effective for me. I know its only a week but had couple coughs and couple times of slight light headedness feeling."

8 / 10
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64 Report
  • Hyzaar...
  • Taken for 2 to 5 years
  • January 25, 2018

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "Be careful with this medication. I caught a bad cold almost a year ago and have been having respiratory issues ever since. I have been diagnosed with asthma and put on the max dose which has helped a good bit but I still feel like this medication caused me to have respiratory issues. The doctors can't find anything wrong other than the asthma. I wish I would have done my research before starting this medicine. I have stopped this medication and will be starting organic medications tomorrow. I am hopeful!"

5 / 10
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36 Report
  • cvdixon
  • Taken for 2 to 5 years
  • September 12, 2017

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I've been on this medication two times now. Both times it's helped lower my blood pressure. I was able to come off of it for about 2 years when I got my blood pressure under control and was keeping it that way, but recently my blood pressure has went back up so my Dr put me back on this medication. My prescription is for the generic brand. I have used both the name brand and generic and I couldn't tell any difference..only price was different. I've had no side effects from this medication, it's worked very well. I would recommend it."

10 / 10
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37 Report
  • Press...
  • August 11, 2017

For High Blood Pressure "After about 2 weeks on this medication, my BP has lowered tremendously, but the small side effects so far seems to worry me, from muscle weakness, shortness of breath, and lots of confusion and memory loss!!!"

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36 Report
  • JMB
  • Taken for 10 years or more
  • September 6, 2018

For High Blood Pressure "I have been on this medicine for at least 10 years. It controls my BP beautifully. I drink coffee with no problem and even Diet Mountain Dew. I have no reaction with the sun either. For my body this is a great medicine. No side effects at all."

10 / 10
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31 Report
  • tcter...
  • July 24, 2009

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "While Hyzaar did lower my blood pressure to normal levels, I suffered from a respiratory problem typically at night time with a gasping for air reflex several times a night. Effective drug but for me, a scary side effect."

3 / 10
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61 Report
  • Jani
  • Taken for 2 to 5 years
  • January 26, 2020

For High Blood Pressure "Was on losartan/hydrochlorithiazide 100/12.5 mg for over 3 years...lowered b/p but had terrible hacking cough and developed asthma in those 3 years while taking daily. Just stopped it per doc instructions and cough has finally went away. Increased hydrochlorithiazide to 25 mg and no losartan at all. B/p lower but not as low as it was on combo. Will continue to monitor but very happy not to be hacking up a lung anymore."

1 / 10
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23 Report
  • Cleob...
  • Taken for 1 to 6 months
  • July 5, 2015

For High Blood Pressure "My doctor put me on benazepril, and I started having a dry cough. That then turned into wheezing and insomia. He put me on losartan-hydrochlorothiazide, and my blood pressure is down with NO side effects. I am also noting that swelling has gone down in my feet and my back pain has vanished as well. I've been on it for a little over a month, and I am thrilled with the results so far. My insurance also covers much more of the cost than the old drug I used, so that's a plus too!"

10 / 10
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39 Report
  • Joy
  • Taken for 1 to 6 months
  • September 22, 2019

For High Blood Pressure "Took 12.5 mg at bedtime for 5 months. Felt like I was going to jump out of my skin. Made me very anxious. Chest and back pain. Did not do much for blood pressure but was on a low dose. Glad to be off this medication."

2 / 10
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22 Report
  • Anonymous
  • June 7, 2010

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "Just started taking this a few weeks ago and its already working for me. Blood pressure went from 200/92 to 140/79 when last checked. Slight feeling of lightheadedness at first but gone now. Also take ibuprofen with no side effects."

9 / 10
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46 Report
  • Cozar
  • Taken for 1 to 2 years
  • January 7, 2017

For High Blood Pressure "After being on losaratan potassium 50mg per day for close to a year did slightly decrease my blood pressure; however I just recently acquired an allergic reaction to it. My lips look like two swollen water balloons. Went to the dr and he took me off of it. It's been close to a week off of this drug and my lips still look like day one of my allergic reaction. I'm told this is a rare symptom, lucky me. Dr offered to put me on prednisone to help with the swelling, but prednisone gives me worse side effects. Suffering through it. Very painful. Dr gave it a week for the swelling to go down, if not ? Luckily my tongue nor my throat swelled up, but still scary nonetheless. Be warned."

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28 Report
  • Anonymous
  • May 17, 2009

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I have been on Hyzaar 100.25 for 2 months, and it has proven to be the most effective of all the other blood pressure medicines I have taken over the last 6 years. I also take a 10mg Norvasc with it every day. I have experienced no side effects. I love it."

10 / 10
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48 Report
  • Frust...
  • Taken for less than 1 month
  • October 23, 2019

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I just started Hyzaar 50 12.5 this morning for high blood pressure. This is the 4th drug that the doctors have tried to use. Within 20 minutes of taking it, I experienced a head rush, as if I had been hit with smelling salts to open up my nasal passage. Then for over 2 hours, I had tachycardia, with my heart pounding. It's been 9 hours since I took my pill, and I am still having tightness in my neck and chest discomfort. When I take a deep breath, it feels like my chest is constricted. It's unpleasant. I am going to see if I can exercise tonight, or if I will be too winded. BTW, I walk all the time and am in good shape. I see the doctor in 3 days. If this keeps up, I need off this medicine, because I don't know how I can live my life with these types of side effects."

5 / 10
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19 Report
  • Mohamed
  • September 24, 2017

For High Blood Pressure "I have been on losartan two and half years. It has lowered my blood pressure to 130/80, I also have kidney disease and my reading of GFR was initially 59 but now it is 47 and it it damaged my kidneys, I also noticed my body takes longer to heal, and muscle loss"

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25 Report
  • cured
  • January 30, 2009

Hyzaar (hydrochlorothiazide / losartan) for High Blood Pressure "I have had high blood pressure for over a year and just started taking Hyzaar 2 days ago and already my blood pressure is 125/75. This is at least 20 units drop in each number and I have not experienced any side effects yet. I feel a lot better."

8 / 10
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46 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.