Skip to main content

Goserelin for Endometriosis User Reviews (Page 3)

Brand names: Zoladex, Zoladex 3-Month

Goserelin has an average rating of 6.8 out of 10 from a total of 64 reviews for the treatment of Endometriosis. 56% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Goserelin

  • Anonymous
  • Taken for 1 to 6 months
  • December 20, 2021

Zoladex (goserelin) "I have had Stage 4 Endometriosis for 20 years, in the past I had Zoladex (no HRT) which stopped my periods and pain, but I went up 3 dress sizes in 6 months. It did seem to help for a while but I ultimately ended up with more surgery (5 in total). Now, 12 years since my last op (and 2 miracle children later), my endometriosis has stuck my ovary to my urethra and bowel, and eating into my bowel wall. I have adenomyosis and a huge fibroid etc. which all just adds up to debilitating periods, 3 transfusions, morphine patches and an inability to work. I'm now back on Zoladex and due my 3rd injection this week, but this time the experience is completely different! I ended up with severe joint pain (poss also complicated by my Raynauds) so started HRT and I now have bled all but 3/28 days with minor flooding (compared to normal) and I feel no difference in size of my uterus. I don't think Zolodex is going to help me this time, could be this combo of fibroids and endometriosis, not sure."

5 / 10
Was this helpful?YesNo
1 Report
  • Chann...
  • June 2, 2021

Zoladex (goserelin) "So I have been struggling with endometriosis since I was 16 years of age and have had the “invisible” disease that was left undiagnosed with endometriosis. I have been suffering for years and have really been on so many trials, zoladex was my last resort. I have only been on it once and there is still severe clotting, heavy bleeding, painful cramps that never go away and it’s constantly me crying in a ball. If anything I’m not going back on this again, I know I’ve only had it once but it’s not helping me at all. I’ve had no morphine to help, no laparoscopy that would help. I have been trembling and crying since last week, been feeling nauseas, angered, tearful, depressed, change of appetite and as someone who has such a short temper it makes my temper worse."

1 / 10
Was this helpful?YesNo
1 Report
  • bgano
  • Taken for 1 to 6 months
  • April 23, 2021

Zoladex (goserelin) "Diagnosed with stage 5 endometriosis at 22. Was put on Synarel nasal spray after surgery in an attempt to reduce leftover bowel endometriosis. Switched to Zoladex after two months on synarel as was worried I wasn't taking it correctly. Loved being on Zoladex, despite the hot flushes, mood swings, bit of weight gain I had no bleeding until Mirena insertion around my 3rd injection. During mirena insertion, gyno noted vaginal nodule meaning the zoladex unfortunately did not work to reduce the bowel endometriosis."

5 / 10
Was this helpful?YesNo
1 Report
  • Zozozo
  • August 7, 2017

Zoladex (goserelin) "This drug has been good, it has stopped my periods & pain I was getting.. the injections aren't as bad as I thought, have had little symptoms, such as; body hair loss, little weight gain, feeling better, slight increase with sweating, lower in sex drive and feeling more bloated then usual."

9 / 10
Was this helpful?YesNo
2 Report
  • FLB
  • Taken for 1 to 6 months
  • April 17, 2023

Zoladex (goserelin) "I’m on my second month of Zoladex, due my third injection shortly and it’s been an absolute godsend so far. I’ve spent since the age of 12 with severely heavy painful periods. Endometriosis has plagued my life as has the effect the menstrual cycle had on my Ehlers Danlos Syndrome, making my hips subluxate and dislocate far more regularly during my period. The pain has been awful. Almost 3 months in and the relief whilst I wait for my hysterectomy is incredible. I’ve had some headaches and hot flashes but honestly I would rather deal with that than the black outs I’ve had every month. I’m 40 now and couldn’t keep going with it."

10 / 10
Was this helpful?YesNo
0 Report

Are you taking this medicine?

  • Celid...
  • Taken for 1 to 6 months
  • June 30, 2018

"I have severe adenomyosis and was put on Zoladex to reduce the size of my uterus, which was causing excruciating pain, nausea, vomiting and IBS type symptoms. The Zoladex has COMPLETELY ERADICATED my terrible symptoms and given me life back. Yes, I had flushes, insomnia and bone pain, but that has improved greatly with add back HRT (Tibolone), except the bone pain, which is worse. However it is a small price to pay for the many benefits. And since starting Zoladex, I have managed to LOSE weight for the first time in years - no diet worked before, but now I have lost 18lbs on Weight Watchers in six weeks. I was so scared of Zoladex, but now I am delighted I tried it!"

9 / 10
Was this helpful?YesNo
0 Report
  • Anonymous
  • Taken for 1 to 6 months
  • March 30, 2023

Zoladex (goserelin) "Been on Zoladex for 6 months now. I am pain-free and feeling so glad and happy and feeling normal for some time and not having to be hospitalized. Hot flashes and weight gain have been my only side effects."

9 / 10
Was this helpful?YesNo
0 Report
  • Lyssa
  • Taken for 1 to 6 months
  • August 13, 2021

Zoladex (goserelin) "At first, reading all of the scary reviews and side effects I was SO scared to try Zoladex for my endometriosis symptoms. I was truly desperate, miserable and out of options at the time. Zoladex saved me (temporarily until I could get my excision surgery )! To start I had terrible cramping and bleeding, after the first two injections ( monthly injections ) I was almost symptoms free from my large cysts and Endo pain . It's not right for everyone, but it CAN work for some ! Hot flashes and mood swings aside, I'll take that over the pain I was in daily."

8 / 10
Was this helpful?YesNo
0 Report
  • Kat
  • Taken for 1 to 6 months
  • September 2, 2022

Zoladex (goserelin) "I was on Zolodex for about 6 months in the hope it would help my endo. Although it didn't, because it turned out it was endo level 5 and everything was stuck to everything else, so, I had a hysterectomy (15 min) and nearly 6 hours of endo removal Feb 2022. Asked my surgeon if I could go back on Zoladex, but only allowed for 6 months which was great because they left my ovaries in. I'm now on Slinda it is awful. Pain has increased again and my mood is like PMS on steroids. I'd like to know if there's a similar med to Zolodex that I can have for more than 6 months at a time. I'm not at menopause age yet, but far out. They should have taken my ovaries out. The pill nor mirena or any of those have ever worked for me. Always made the pain worse since I was 15. I've been lucky enough to have one baby and I'm so grateful. I just don't want to be like king Kong all the time. Thanks, any suggestions are welcome"

8 / 10
Was this helpful?YesNo
0 Report
  • CBL
  • Taken for 6 months to 1 year
  • January 25, 2022

Zoladex (goserelin) "Diagnosed at 29, Zoladex for 6 months. Endo pain only subsided since you do not get periods while taking this drug. However, I experienced terrible inflammation and water weight gain, my clothes stopped fitting after the second injection. I workout and eat healthy mind you. I am constantly fatigued, and lack motivation. Brain fog is real on this drug. The hot flashes are so miserable, couple it with the insomnia and it has been a miserable 5 months. The cellulite and weight gain has been the hardest for me, since I am into fitness. I feel like I’m in someone else’s body. I get headaches daily and usually suffer a migraine within 24 hours of a dosed injection. I’m on my last dose and I’m hoping after I can get back to my normal self. I dealt with sciatic pain with the endo, it’s not as bad but still around. I’m still trying to figure out if this treatment has been worth it. We shall see by April."

5 / 10
Was this helpful?YesNo
0 Report
  • Swissa
  • Taken for 1 to 6 months
  • March 29, 2022

Zoladex (goserelin) "This is my second month for this injection, the first month was so bad. I had too much side effects, night after my injection I had hot flashes and painful bones especially on my ankles. And day after day it gets worse had dizziness everyday, constant tired without reason and super fatigued, muscles pain, super vaginal dryness and couldn’t walk longer bcoz my feet and legs hurts so bad. But there’s also good side effects like I’m totally no more bleeding/period or even spotting so it means no pain."

7 / 10
Was this helpful?YesNo
0 Report
  • Anna
  • Taken for 1 to 6 months
  • January 25, 2020

Zoladex (goserelin) "This is the first time in 25 years I've been pain free and no periods, changed my life whilst I await my hysterectomy"

10 / 10
Was this helpful?YesNo
19 Report
  • Deedzx
  • Taken for 1 to 2 years
  • December 1, 2018

Zoladex (goserelin) "It work, yes... but the side effects are the worst. Insomnia, bone pain, nausea, hot flashes, and weight gain... I hate it, but it's better than endometriosis"

8 / 10
Was this helpful?YesNo
9 Report
  • Anonymous
  • July 11, 2011

Zoladex (goserelin) "Love it! The hot flashes aren't much fun, but they're worth having no period or pain!"

8 / 10
Was this helpful?YesNo
16 Report
  • Anonymous
  • May 23, 2023

Zoladex (goserelin) "Can anyone give me advice on how to lose weight whilst taking Zoladex? I've put on so much weight and have such a swollen stomach most days. This is awful."

Was this helpful?YesNo
2 Report
  • Pia
  • February 4, 2021

Zoladex (goserelin) "No more pain no monthly period after injection of zoladex, back to normal life, hot flushes for two years but bearable I really recommended this zoladex from 2009-2020 no pain thank You God."

Was this helpful?YesNo
3 Report
  • Angels
  • Taken for 1 to 6 months
  • February 28, 2021

Zoladex (goserelin) "3 months in pain free yes, but feel completely exhausted. Also weight gain"

4 / 10
Was this helpful?YesNo
1 Report
  • Angel
  • February 11, 2021

Zoladex (goserelin) "I’m on my 3rd month pain wise 0 which is amazing . However I feel exhausted I mean chronically fatigued"

6 / 10
Was this helpful?YesNo
1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Endometriosis

Care guides

Symptoms and treatments

Medicine.com guides (external)