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Efudex and Bleeding: What Users Say

Bleeding: mentioned by 5 users (3.9%)

Based on user experiences from 127 Efudex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 32.3%
itching 28.3%
redness 17.3%
swelling 11.0%
burning 9.4%
blisters 6.3%
discomfort 5.5%
peeling 5.5%
rash 5.5%
bleeding 3.9%

Reviews for Efudex

Commonly mentioned side effects
  • Lar...
  • March 5, 2013

For Keratosis "Used the product on my face for 6 weeks twice a day for two days every week. Depending on the extent of sun damage, the effects are dramatic and nasty looking. After the 2nd week, the treated area looks like a bad sunburn, it itches, peels, weeps, bleeds and burns. But the results after stopping for 3-4 weeks are very good."

8 / 10
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194 Report
  • Gra...
  • Taken for less than 1 month
  • January 15, 2020

For Actinic Keratosis "I am using Efudex, and the spots were getting raised and crusty as expected, but then it got damp in the shower and came off with a bit of bleeding. It has settled down now. But I was worried if this has set back the process. I would appreciate your comments."

8 / 10
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61 Report
  • Jof...
  • Taken for 6 months to 1 year
  • August 27, 2019

For Keratosis "Treatment with Efudex on both arms for keratosis caused damage, had a bad reaction creating an auto-immunity situation; still being treated by a dermatologist after 12 months. Itching unbearable on arms, bleeding after scratching and left with a watery mess. Relief from ice packs helps and then moisturizing. Treatment from Prednisolone, Cyclosporin lasts for a few weeks and then I break out again. Been around this way 6 times now! Efudex: seek all the info you can before treatment."

1 / 10
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61 Report

Frequently asked questions

  • In...
  • Taken for less than 1 month
  • April 8, 2020

For Actinic Keratosis "I spent years in the sun, scuba diving and hiking in Mexico and Arizona. For years, I've constantly had to use lip balm because my lips were so dry. I tried many products, and they never worked. My lips would crack and peel all the time. Just recently, I got diagnosed with actinic cheilitis. I have been prescribed Efudex 5% once a day for 3 to 4 weeks. I am at Week 2 and experiencing severe, almost unbearable burning pain because of deep sores with massive amounts of oozing and crusting and now bleeding, tightness, and severe dryness. I will try to endure another week, but I think I would rather have surgery any day than this."

3 / 10
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44 Report
  • Sun...
  • Taken for less than 1 month
  • January 27, 2020

For Keratosis "Dermatologist prescribed Efudex for keratosis, 1 week on and 3 weeks off x 4 to treat my face, but said not to apply on chin. After a few days, freckles appeared, and by day 7 today, my skin feels quite irritated, itchy, and a slight sting - especially the sides of my nose. One spot above my eyebrow has bled slightly last night and tonight after washing my face. My dermatologist said I could continue to wear foundation but to wait 15 mins after applying cream."

9 / 10
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34 Report

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