Enhertu and Diarrhea: What Users Say

• bem...
• Taken for 1 to 6 months
• June 13, 2023

For Breast Cancer, Metastatic "Had 2 treatments with Enhertu. The side effects were bad and did not go away for a long time: dizziness, jitteriness in the entire body, fatigue, weakness, diarrhea, sick stomach, felt unwell all over and inside the body. Never, never would have another treatment with Enhertu!!"

• Ano...
• Taken for 6 months to 1 year
• June 24, 2025

For Breast Cancer, Metastatic "Was told with LMD I had 3-6 months to live. Been on Enhertu for 10 months. One treatment every 21 days. I get Emend and steroids with the infusion. These stop the side effects. I have not had any nausea or vomiting, but have had some constipation and sometimes diarrhea. It's been the easiest of all the meds I've tried. It seems to be working systemically, my LMD has been stable, no progression so far. Grateful to have something that is finally working."

• Ano...
• Taken for 1 to 6 months
• April 3, 2025

For Breast Cancer, Metastatic "Had done #6 cycle and dosage had reduced to 80% after the 2nd infusion due to liver dysfunction. The side effects are bowel system haywire, nausea, constipation, diarrhea, skin rashes, body heat, hair loss, and so on. The side effects are not getting better after each cycle. So helpless!!!!"

• Anonymous
• Taken for less than 1 month
• April 27, 2023

For Stomach Cancer "As a patient, I can't rate the efficacy of this medication because I have had only one round. After many rounds of chemotherapy using other medications, I can say that the side effects of this medication were much worse and enduring after one round. Severe diarrhea, debilitating fatigue, debilitating nausea, and stomach pain. Side effects began on day four and lasted until day 7. Will take half dose next round but will continue on the regimen as prescribed for now. One lousy week out of three is not acceptable to me. If the next round is as bad, I will cease using this medication. The oncologist stated that while I tolerated other regimens better than most, I tolerated Enhertu worse than most."

• Ano...
• Taken for 1 to 6 months
• April 3, 2025

For Breast Cancer, Metastatic "Had done #6 cycle and dosage had reduced to 80% after the 2nd infusion due to liver dysfunction. The side effects are bowel system haywire, nausea, constipation, diarrhea, skin rashes, body heat, hair loss, and so on. The side effects are not getting better after each cycle. So helpless!!!!"