Enhertu Alternatives Compared
| Enhertu | Opdivo | Lumakras |
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| Enhertu (fam-trastuzumab deruxtecan) | Opdivo (nivolumab) | Lumakras (sotorasib) |
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Prescription only
Prescribed for Breast Cancer - Metastatic, Stomach Cancer, Non-Small Cell Lung Cancer, Breast Cancer. Enhertu may also be used for purposes not listed in this medication guide. |
Prescription only
Opdivo is an immune checkpoint inhibitor that may be used to treat many different cancers including melanoma, liver cancer, and lung cancer. Fatigue, skin conditions, a cough, upper respiratory tract... View more |
Prescription only
Prescribed for Non-Small Cell Lung Cancer. Lumakras may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Enhertu (fam-trastuzumab deruxtecan) | More about Opdivo (nivolumab) | More about Lumakras (sotorasib) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Enhertu has an average rating of 6.8 out of 10 from a total of 8 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 13% reported a negative effect. |
Opdivo has an average rating of 4.8 out of 10 from a total of 78 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 53% reported a negative effect. |
Be the first to share your experience with this drug. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Enhertu side effects in more detail. |
See also: Opdivo side effects in more detail. |
See also: Lumakras side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Enhertu prices |
View all Opdivo prices |
View all Lumakras prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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136.8 hours |
640.8 hours |
5 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 155 drugs are known to interact with Enhertu:
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A total of 19 drugs are known to interact with Opdivo:
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A total of 459 drugs are known to interact with Lumakras:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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N/A |
December 22, 2014 |
May 28, 2021 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.