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Enhertu and Constipation: What Users Say

Constipation: mentioned by 4 users (11.1%)

Based on user experiences from 36 Enhertu reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 33.3%
nausea 30.6%
hair loss 19.4%
diarrhea 13.9%
constipation 11.1%
dizziness 8.3%
stomach pain 8.3%

Reviews for Enhertu

Commonly mentioned side effects
  • Ano...
  • Taken for 6 months to 1 year
  • June 24, 2025

For Breast Cancer, Metastatic "Was told with LMD I had 3-6 months to live. Been on Enhertu for 10 months. One treatment every 21 days. I get Emend and steroids with the infusion. These stop the side effects. I have not had any nausea or vomiting, but have had some constipation and sometimes diarrhea. It's been the easiest of all the meds I've tried. It seems to be working systemically, my LMD has been stable, no progression so far. Grateful to have something that is finally working."

9 / 10
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3 Report
  • Ano...
  • Taken for 1 to 6 months
  • April 3, 2025

For Breast Cancer, Metastatic "Had done #6 cycle and dosage had reduced to 80% after the 2nd infusion due to liver dysfunction. The side effects are bowel system haywire, nausea, constipation, diarrhea, skin rashes, body heat, hair loss, and so on. The side effects are not getting better after each cycle. So helpless!!!!"

5 / 10
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3 Report
  • Ano...
  • Taken for 1 to 6 months
  • April 3, 2025

For Breast Cancer, Metastatic "Had done #6 cycle and dosage had reduced to 80% after the 2nd infusion due to liver dysfunction. The side effects are bowel system haywire, nausea, constipation, diarrhea, skin rashes, body heat, hair loss, and so on. The side effects are not getting better after each cycle. So helpless!!!!"

5 / 10
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0 Report

Frequently asked questions

  • Ano...
  • Taken for 1 to 6 months
  • August 17, 2025

For Breast Cancer, Metastatic "Hair loss, stomach pain, fatigue, nausea, back pain, constipation, increased hunger, mouth sores. It takes 9-10 days out of the 21-day cycle to recover after each infusion."

6 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.