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TriNessa Lo and Depression: What Users Say

Depression: mentioned by 5 users (10.6%)

Based on user experiences from 47 TriNessa Lo reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

acne 51.1%
mood swings 23.4%
headaches 17.0%
nausea 14.9%
cramps 12.8%
anxiety 10.6%
depression 10.6%
weight gain 10.6%
bleeding 8.5%
heavy periods 8.5%

Reviews for TriNessa Lo

Commonly mentioned side effects
  • Jen...
  • Taken for 1 to 6 months
  • January 13, 2018

For Birth Control "I'm a 36-year-old and hadn't been on hormonal BC for 6 years before I started TriNessa Lo for BC. I've had many side effects. I had daily nausea that felt like morning sickness all day, every day. I only had relief during my period. I couldn't tolerate foods that I normally consume. Also, certain scents, like air fresheners, made me feel sick. I had occasional headaches and broke out with a lot of acne. My sex drive was nonexistent. I also felt significantly depressed near the end of my cycle before my period started. I decided to stop taking it after 3 months of use. Now, 2 weeks after stopping, all those side effects are gone. Bad experience for me!"

3 / 10
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  • Joj...
  • November 17, 2017

For Birth Control "The time I was on TriNessa was horrible. I had major mood swings, lost a lot of weight, got really depressed, and felt like a totally different person. I also got migraines once a week from the start of the pill until I finally decided on changing it."

1 / 10
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1 Report
  • M C...
  • Taken for 1 to 6 months
  • December 1, 2017

For Abnormal Uterine Bleeding "Out of the 3 pills I have taken (the others being Microgestin Fe and Tri Lo Sprintec), Trinessa is probably the best. Microgestin caused not only constant constipation and the worst depression I've ever experienced. I switched to Trinessa, and these problems lessened within the first month. Trinessa did give me some nasty forehead acne and mood swings, but these also disappeared relatively quickly. My only real complaint is that until the 5th month on it, I would spot for a week straight before my placebo week. My flow was pretty heavy, but no terrible cramps accompanied it."

7 / 10
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2 Report

See also:

  • lll...
  • Taken for 1 to 2 years
  • April 26, 2018

For Acne "Trinessa Lo (generic Ortho Tri-Cyclen) helped my mild to moderate acne some, but not enough. I ended up going on Accutane. While taking this, I noticed I was anxious, depressed, and just not myself. I often felt moody and irritable, cried for no reason, no longer wanted to be around my boyfriend, and was just angry. I stopped taking this pill and noticed a drastic difference for the better. I am so much happier, less anxious, less depressed, and my relationship is back to normal. I feel like myself again. This stuff will mess with you. The only good thing was my usually painful periods were predictable and cramps were mild."

5 / 10
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1 Report
  • Nic...
  • Taken for less than 1 month
  • July 10, 2018

For Birth Control "This birth control added severe anxiety and depression to my life. I had to stop after a few days. Will stay on non-hormonal IUD."

2 / 10
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3 Report

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