Skip to main content

Vyepti for Migraine Prevention User Reviews (Page 2)

Vyepti has an average rating of 5.2 out of 10 from a total of 33 reviews for the treatment of Migraine Prevention. 39% of reviewers reported a positive experience, while 39% reported a negative experience.

Reviews for Vyepti

  • MRano
  • Taken for 2 to 5 years
  • May 12, 2022

"Vyepti has been wonderful for controlling my chronic migraines. The only side effects that I get are dry mouth and bruising at the infusion site. I get the maximum dose, infused over half an hour, every three months. The third month, I start to have more break-through migraines, but they aren't as severe as usual. I get the infusion done at the hospital specialty clinic, so it doesn't cost me anything."

9 / 10
Was this helpful?YesNo
13 Report
  • Amazed
  • Taken for less than 1 month
  • August 24, 2023

"My migraines started in 5th grade. I struggled through them for years, being prescribed a variety of mostly ineffective medications. I am now 71 years old and for the last few years I've been under the care of a neurologist who is a headache specialist. Before other preventatives, she tried me on two other CGRP antagonists, with mixed results. She recently switched me to Vyepti. I was told that it might take 2-3 infusions to notice a difference, but some people get relief much sooner. It's been two weeks since my first 100mg Vyepti infusion, and no migraines! I was having about 15 migraines per month before Vyepti, so this is like a miracle for me. I doubt that this is a coincidence. And no side effects."

10 / 10
Was this helpful?YesNo
6 Report
  • Still...
  • Taken for 1 to 6 months
  • April 5, 2023

"I told my first round of 100 mg on 2/26/23. Two days later I began getting cold symptoms and sinus pressure and stuffiness. 6 weeks later I still feel stuffy and constantly blowing my nose. I woke up with a headache every day, which I wasn’t experiencing before but I didn’t have any migraine symptoms for about 5 weeks. I do feel that it changed my mood. I was depressed or sad but not happy either just felt neutral. Still not sure how I feel about it. I may go back to ajovy."

4 / 10
Was this helpful?YesNo
8 Report

Frequently asked questions

  • Walki...
  • Taken for 1 to 2 years
  • October 2, 2023

"I have been on Vyepti (300mg every 3 months) for over a year and it's the only thing that has helped me in the last 8 years. My migraines are reduced by 90% until the last two weeks of the medication, and my daily headache pain goes from a 9 to a 5, which is a huge difference. I get the runny nose side effect for about a day after the infusion, but other than that, no side effects! I recommend trying it for those who have tried 50 other things."

10 / 10
Was this helpful?YesNo
5 Report
  • BR549
  • Taken for 1 to 6 months
  • February 13, 2024

"I’ve had migraines since I was 16 and am now 46. Vyepti is the only preventive medicine that has ever worked for me. I just had my 2nd dose. Only had 3-4 migraines since receiving my first infusion, and my Imitrex took care of those much faster than normal; they didn’t end up lasting 3+ days. It’s been absolutely life-changing. No noticeable side effects—think my weight gain has much more to do with me than my Vyepti."

10 / 10
Was this helpful?YesNo
2 Report

Are you taking this medicine?

  • Shamara
  • Taken for 6 months to 1 year
  • May 18, 2024

"I am absolutely amazed at the results of this medication. I have had migraine headaches for most of my life, since I was 8 yrs old. I had a head injury and I have had horrible headaches since. I have taken almost everything on the market for them: Imitrex, the 'Triptans', Aimovig, most of the relief meds, the vitamin supplements, the natural route... everything. I mean I literally have tried it all. This has made an amazing difference in my life. To wake up & actually NOT have a headache is absolutely wonderful. I hadn't known that life in so long, I cried when it happened. I am on 300 mg now as the starting dose helped but didn't work long. Now I only get a headache when it's the week of my infusion, which is amazing. I will definitely take that compared to what I had before. I also use Nurtec as my relief med, which the combination is completely unmatched. I am so grateful for this new medication."

10 / 10
Was this helpful?YesNo
0 Report
  • mrhot...
  • May 18, 2024

"During my second infusion that was 300mg, I got a migraine. During my first 3 months of 100mg I saw improvement in weather-related triggers and odors. But I was more light sensitive, especially to the TV. My doctor gave me Ajovy samples to supplement the Vyepti unit I could go to 300mg."

6 / 10
Was this helpful?YesNo
0 Report

More FAQ

  • Thead...
  • Taken for 6 months to 1 year
  • May 24, 2021

"Been on the drug for almost one year. I'm currently down to maybe one migraine a month! So Happy with these results!"

Was this helpful?YesNo
27 Report
  • Itchy
  • Taken for less than 1 month
  • June 16, 2022

"Not so great, I had an allergic reaction and ongoing migraine for days accompanying the allergic reaction. I am allergic to a lot of things though. 100mg dose."

1 / 10
Was this helpful?YesNo
19 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 12, 2022

"Miracle drug. Lessens my headache days and severity of my migraines. No dud effects at all. Wish I could have found this years ago"

10 / 10
Was this helpful?YesNo
12 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Migraine Prevention

Medicine.com guides (external)