Denosumab for Osteolytic Bone Metastases of Solid Tumors User Reviews

• Jef...
• Taken for 1 to 6 months
• February 8, 2020

Denosumab "I just had my third dose of Xgeva, I have them monthly for metastatic breast cancer. The first two times I had some lower back pain and minor aches and just feeling yucky for 24 hours. I had my third shot yesterday. I woke up after midnight in a lot of pain. My bones, muscles, and joints hurt. I was able to fall back to sleep but felt awful the next day and had more localized pain where my cancer is. When I related this to my doctor's nurse, she was surprised because she had never heard of this. I've read quite a few reviews of other patients experiencing the same thing. I'm uncertain as to continue taking this medication."

• Kim...
• Taken for 2 to 5 years
• June 8, 2019

Denosumab "I have been on Xgeva for the last three years, I have breast cancer stage 3. I receive the shots every 3 months, and I take a calcium pill every day. I don’t have pain from the Xgeva. I only get a burning sensation with the shot. If I feel cramping in my legs, I eat a banana every day. I don’t know how long it is effective. Does anyone else know how many years or how long you can take it or how long it is effective for?"

• Unl...
• Taken for 6 months to 1 year
• November 16, 2019

Denosumab "I had been having injections of Xgeva for 7 months; I never had any difficulty - after my eighth injection, after two days, I developed horrific pains at the sites of very old bone and joint injuries - I cannot explain why the difference - even my hands hurt! I am very reluctant to take any more of this drug."

• Anonymous
• Taken for 1 to 2 years
• March 23, 2024

Denosumab "I have been taking Xgeva for 1 1/2 years and the metastasis on my back has greatly improved with no side effects. I am taking vitamins C, D3, and Calcium. My oncologist and I are very satisfied so far. Thanks."

• Mug...
• Taken for 1 to 2 years
• August 12, 2021

Denosumab "I have prostate cancer that metastasized to the bone. This would be stage 4 prostate cancer. The prostate was removed by surgery 10 years earlier. I have been getting Xgeva injections for about 14 months. The pain I notice is in both upper legs and my low back. Pain could be from cancer or Xgeva. Just don't know. The back hurts a lot. I have learned to pre-medicate with Aleve or Tylenol about 2 hours before going to bed. This usually works. I go to bed without pain, but it comes on as I lay in bed, so I catch it early."

• Anonymous
• Taken for 6 months to 1 year
• June 12, 2012

"I have breast cancer with metastasis to the bone. Prior to taking denosumab, I was receiving Zometa, approximately 2 years on a monthly basis. One positive element is that this is being given subcutaneously, saving my veins, also, it is not so hard on my kidneys. I do experience itching and back pain, but this only lasts about 1 week after the subcut. I have been receiving the injections approximately 6 months, every month. I also take Aromasin and was diagnosed in April of 2007. My tumor marker is low at 22, remains at that number after making the switch from Zometa to denosumab."

• Anonymous
• March 23, 2024

Denosumab "I have been taking Xgeva for 1 1/2 years and the metastasis on my back has greatly improved with no side effects. I am taking vitamins C, D3, and Calcium. My oncologist and I are very satisfied so far. Thanks."

• Wee...
• June 20, 2018

Denosumab "Terrible side effects: bone pain, weakness, groin, and hip pain."