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User Reviews for Clindamycin to treat Skin or Soft Tissue Infection

Also known as: Cleocin, Cleocin Phosphate, Cleocin Pediatric, Cleocin HCl, Cleocin Phosphate ADD-Vantage

Clindamycin has an average rating of 5.9 out of 10 from a total of 90 ratings for the treatment of Skin or Soft Tissue Infection. 47% of reviewers reported a positive effect, while 36% reported a negative effect.

Clindamycin Rating Summary

5.9/10 average rating

90 ratings from 97 user reviews.

Compare all 136 medications used in the treatment of Skin or Soft Tissue Infection.

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Reviews for Clindamycin

Brill · Taken for less than 1 month June 1, 2020

“I was prescribed 150mg clindamycin for an armpit boil. I just had slight stomach discomfort, no diarrhea or any complications. Everyone's system reacts differently to the medication. I made a mistake by looking at reviews before taking it. It's not always a horrible experience.”

9 / 10
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Katie September 6, 2020

“I saw all the horrible reviews. But I had no choice. I'd already been on amoxicillin for 7 days for a dental abscess and had to try clindamycin. Let me say I have EXTREME anxiety and HATE taking anything. So I was nervous. Anyway I had read some people said drink LOTS of water with it and take a probiotic, so I did. I drank 30oz with every dose (3 times a day) and took a probiotic halfway between doses 2 and 3. I also sipped water throughout the day (no juice, coffee, soda etc. I had almost ZERO side effects. I did notice for about an hour after each dose, I felt a little dizzy/out of it. Nothing major (could have just been my anxiety too). I also did use the bathroom more often, but honestly with my level of anxiety I was not surprised. That was it. And it cleared up my infection totally! I will continue the probiotics and lots of water at least for a month to be sure. But this stuff works. Don't let the reviews scare you. I think lots of water is key.”

10 / 10
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CrazyPhoenix January 18, 2019

“I've never posted a review before but wanted to reassure people that are freaking out reading the scary reviews that not every experience is like that. I was having panic attacks when taking the pills because of reviews I'd seen. My anxiety about it made me feel sick this week, not the pill. Made sure to drink 2 big glasses of water when taking a pill.....ate before taking it...had yogurt everyday and didn't lay down or recline for one hour after taking it. Other than getting mild diarrhea a few times I haven't experienced any other side effects. I was taking 300mg/3x a day for 7 days. I take my last pill tonight.”

7 / 10
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Kat2015 September 19, 2015

“I had a serious Cellulitis infection in my leg this year (Summer of 2015) and since I am allergic to Penicillin, I asked the doctor for Clindamycin. It worked well! I didn't have any side effects that I could notice. I am still on the watch for any tummy trouble though, since I read the FDA warning about C-diff and this drug. Hopefully I won't get that. But as for the Cellulitis, the Clindamycin completely resolved it, I am so happy to say. I tolerated the drug well. I drank lots of water while on it and when taking it. That's very important. So happy that this antibiotic worked so well. The prescription was for 300mg/pill 4 times per day.”

10 / 10
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Dallas Alice August 20, 2016

“Had a deep gum abscess, not tooth, but gum, from a piece of popcorn. Dr. Rx was 300mg 3x a day, for 10 days. No problems.. You HAVE to drink tons of water when taking the pill and all day long. Why? To flush out the toxins. When STRONG antibiotics work, they KILL the good and bad bacteria. That die off is called a "Herxheimer" reaction. Thus, the headaches, eye aches, etc. So, up your intake of WATER to help. Then, take probiotics, kefir and yogurt because the GOOD bacteria are killed off in your gut, hence severe diarhhea. C Diff is a dirty hospital issue, it's their big secret, but probiotics will reestablish the GOOD bacteria, very quickly. Hang in there, it is the best medicine ever....”

10 / 10
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Julia S. August 8, 2014

“I am allergic to many antibiotics including amoxicillin, and this is after taking it many times before and suddenly developing a reaction. I was given Clindamycin(doc said it is one of the milder antibiotics) for 5 foot/ankle/calf surgeries. Months of my surgeries. Aug., Sept., Dec. 2013 and Aug. 7 2014 (last night). The doctor didn't want me to develop an infection which is why he prescribes it. It is now the ONLY medication that works for me. PLUS, I have a medium size hiatal hernia, GERD and bad acid reflux and esophagitis. The previous 4 surgeries I had to take the capsules 3 x a day for 10 days and this last surgery 3xday for 3 days. THE KEY TO TAKING CLINDAMYCIN IS TO DRINK ALOT OF WATER AFTER SWALLOWING IT. I never had one problem”

9 / 10
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Scared to death January 13, 2020

“This is my true experience! This is an awful drug. I developed severe infection after a tooth extraction. Family physician who sent me to emergency fearing deep space infection. Incredibly grateful to him for his care integrity of human life. I get to emergency and I'm put on IV clindamycin the doctor tells me how great the drug is and says nothing about the side effects. I return the next day to the hospital for a second round of clindamycin doctors still not considered my bowel condition and when I say I'm itchy and burning I'm ignored. Then given a prescription to fill of the drug and begin taking orally at home. Three days later I go back to emergency. Days later loose stools continues to get worse Clear jelly like matter and mucus alternating are coming out. I return to emergency nine days later I'm told I have flu. I tell the doctors about the drug...they ignore me. Send me home. It's nineteen days now and I feel like my bowel is going to explode. Going back to emergency”

1 / 10
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Frequently asked questions

Anonymous · Taken for less than 1 month August 20, 2012

“I read the reviews before taking the medicine and almost did not take it. The reviews scared me but I had to give it a chance and I am glad I did. I did not experience anything mentioned in the reviews. It cleared my skin infection in 7 days. I did take it on a full stomach and ate 2 yogurts with live cultures daily to keep the normal balance in my stomach. I think this really helped.”

10 / 10
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Ceceily · Taken for less than 1 month April 12, 2020

“I had oral surgery on 4/9 and was prescribed this clindamycin medication. Twenty minutes after taking the first pill, i had a painful knot in my throat/chest that made me burp and it felt like I could puke any minute. I thought maybe it was stuck in my throat. I took my 2nd dose about 7 hours later and same thing. I called my oral surgeon yesterday morning and told him of this side effect. He told me to eat yogurt before taking it and that should help. He was right. I just eat half a cup of yogurt and then take this pill and the knot in my throat is gone. I hope this helps others who are having the same issue.”

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JayEll48 December 11, 2013

“I was prescribed 10 days of oral capsules of this medication after other medicines did nothing for a moderate skin abscess. Clindamycin is a strong antibiotic, and diarrhea is often a side effect. To help prevent this from happening, I took Acidophilus capsules. Yogurt does not provide enough Acidophilus--you really need the capsules. I took Clindamycin every 6 hours, so in between (that is, 3 hours after the antibiotic) I would take an Acidophlius capsule. I didn't bother getting up in the night to do this. I believe the Acidophilus prevented my getting diarrhea while the antibiotic cured the infection. You can get Acidophilus in health food stores in the refrigerator case.”

9 / 10
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mj671 October 15, 2013

“Took clindamycin, two 150 mg every 6 hrs for 7 days. I was hesitant to take this because I've had C. diff before from taking Cipro several months ago. I had cellulitis from bee stings and I had no side effects from taking clindamycin...except to make sure to have food in your tummy when taking this because it does give heartburn if your tummy is empty. Other than that, I am thankful that I had no side effects from this. I'm sorry to hear those who are extremely sensitive to this strong antibiotic but it has surely helped cute my cellulitis.”

8 / 10
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kuno78 · Taken for less than 1 month August 10, 2020

“If you are bipolar, do NOT take clindamycin unless you want to end up in the hospital. This clindamycin has caused me off the charts mania/anxiety/panic that left me with suicidal ideation. The stomach cramps and heart palpitations is also something I could do without. Miserable, bed bound, and hoping for it all to finally end. There is ZERO reason why this junk should be on the market. It literally destroys your digestive system. It did nearly get rid of my boil, but I had to stop before ending up inpatient.”

2 / 10
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Kristin · Taken for less than 1 month August 22, 2018

“DO NOT TAKE THIS DRUG! I was prescribed this drug for what a Dr thought was a staph infection on my skin. It wasn't. It was just an irritation and this Dr OVER reacted and didn't culture it. I was prescribed it for 7 days, twice a day. THIS DRUG RUINED MY LIFE. I took only 3 pills realizing that this really wasn't staph and my body was healing it on it's own. About 3 weeks later, I was sicker than I've ever been. Intense stomach pain, and water coming out of both ends every 15 minutes. I was diagnosed with severe C DIFFICILE (c diff). My gastroenterologist who treated me said that had I taken more, it would have killed me. I was treated for c diff for 7 months. After taking all of the drugs to treat c diff we almost did a fecal transplant. This drug shouldnt even be on the market. There are so many other drugs out there that won't hurt you the way this does. I am warning you all!!!!!!!!”

1 / 10
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Dee · Taken for less than 1 month August 3, 2019

“clindamycin caused excruciating esophageal and gastric pain, nausea, and a general feeling that I was going to die. I woke up in the middle of the night with extreme chest pain and couldn't even get out of bed, and eventually passed out. I was genuinely surprised to be alive when I woke up the next morning. I could only get through three days before the side effects became this severe and they only got worse and worse. It took more than 8 months to fully recover and I was living with severe heartburn, weakness, nausea, and inability to eat or drink without severe pain. Thousands of dollars of tests, additional drugs, probiotics, and self medication later it eventually got better. Upper endoscopy revealed severe gastritis which I know was directly caused by clindamycin. Never again.”

1 / 10
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Pinkone1 January 15, 2017

“Hi , I got Clindamycin 300mg 3 times a day. I have swollen skin infection on my cheek. I have read the reviews here before I took the capsule. I was too scared to take it, but due to my infection, I must go through with it. I am on my fourth capsule. I took some of reviewers advice, in which I drank a glass of water before my meal- eat half of my meal- then took the capsule- with glass of water then finishes my meal. Drink another glass of water after. Not to lay down for an hour. Better a little bit more time cause it takes time to digest it. Then about two hours later I ate yoghurt- activia probiotic. I take my capsule in the morning, noon, and evening around 6-7 p.m. Then I have plenty of time to rest over night.”

9 / 10
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Infecty McFectison · Taken for less than 1 month December 18, 2014

“I have taken this twice in the past for dental and skin infection, and am currently on it again, all for dental issues. I developed C. diff after both previous cycles of taking this medicine, with the most recent being near-fatal. That said, it's the best medicine for treating broad-spectrum serious infections, so it did work on the initial infection well each time. I have also developed a mild blistery rash on my chest and upper arms while taking this in the past, but it cleared up when finishing the meds. My only major warning: if you develop C diff. symptoms in the weeks or months following this medication (several watery/loose stools per day, weakness, stomach pain, vomiting, nausea), insist your doctor test a stool sample to culture for C. Diff.”

9 / 10
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Domne26 · Taken for less than 1 month April 29, 2019

“Took this 300 mg three a day for 10 days. My infection was gone after about 48 hours. Minimal side effects. Maybe a little diarrhea but that’s it. I took with yogurt. I don’t swallow pills so I had to empty the capsule. DO NOT mix with the yogurt. This is the worst tasting stuff you can imagine. You will need to put a little in the middle of a spoon of yogurt to down this.”

10 / 10
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More FAQ

Sungoddess · Taken for less than 1 month February 9, 2020

“I was prescribed clindamycin for a horrible infection of my finger that was swollen and I couldn't bend it. I had cramps and diarrhea the same day I started on it. I took a 300mg dose every 8 hours for 10 days. I broke out in hives on day 4 or 5. Had the worst heart burn I've ever experienced. Also felt like I was getting a yeast infection. Then 2 days after finishing the mess I woke up with every joint from head to toe hurting like never before. Every muscle ached also from head to toe for 2 days . Horrible headache, lethargic and weak and sweating and clammy and absolutely miserable. These symptoms were worse than any flu I'd ever had. I could barely get out of bed for 48 hours. Then the body aches subsided quite a bit. I kept having chronic headaches, nausea, diarrhea still going on since day one. Still clammy and sweaty and weak. My GI system hurts from sternum to my butt. I will never take this pill again !!”

1 / 10
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Momof12 April 7, 2017

“I was on IV for 4 days and then switched to oral 4x a day. When I started taking it orally I got bad heartburn, felt like something was stuck in my throats and sometimes it hurt in my chest. I questioned the pharmacist and she told me to take an anti acid 1/2 hour before my dose (one was good for 2 doses) and drink lots of water. I did this and had no more problems.”

10 / 10
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Selli September 15, 2019

“I made sure to check with the Dr & the pharmacist on the correct way to take the medication because I know many antibiotics can upset your stomach if taken on an empty stomach. I was told to eat something before taking it & to expect diarrhea. Before I took it, I also read the little pamphlet that came with the medication from my pharmacy. The directions said to take with a little bit of food & to drink a full 8 oz. water w/the pill AND to not lay down for 10 min after. I followed those rules & did not have diarrhea or any other side effects. The only side effect that I did have is a ridiculously awful taste in my mouth. I wouldn't even call it metallic but it tastes like the worst morning breath x10. Even brushing and rinsing with mouthwash hasn't gotten rid of it. My last dose was over 24 hours ago and I still have the taste in my mouth. Hoping it will go away soon. Otherwise, I have no issues with this antibiotic. I was on 300mg 4x a day for 10 days and it worked for my issue!”

8 / 10
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CMiLLO · Taken for less than 1 month February 1, 2016

“I was prescribed 300mg of clindamycin 4xs a day for 7 days. I am 1/2 through the course. I read many of the unfavorable reviews as well as the information from the pharmacy. I was terrified. My Doctor did tell me to take the medication with a probiotic. After doing some research on which probiotic to take I went back to the pharmacy to pick up those pills as well. As others have stated you MUST take this med with plenty of water. After the first 4 pills I did have a slight headache and noticed my eyes seemed red and slightly irritated. I pushed the next dose out by 2 hours and increased my water intake. I haven't had any more issues (so far). I will update after I complete the full dosage. *I would recommend taking the probiotic.”

6 / 10
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Worked Well December 21, 2015

“I was prescribed 300 mg 3 times per day for 7 days. This was the fourth antibiotic I was placed on in two weeks because nothing else was working. It did its job well. The only noticeable side effect was a slight headache on and off. I heeded the warnings on here though. I drank 16 ounces of water each time I took a pill and always at meal time. I did not lay down for at least an hour afterward. I ate one yogurt in the morning and took a probiotic in the evening. Also, I had suspected a sinus infection that had never cleared up for over a year. This medication proved me right because I feel better than ever.”

10 / 10
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c · Taken for less than 1 month July 31, 2019

“I had a tooth infection and I'm allergic to most antibiotics so my doctor told me he had to give me 'one that would be hard on the stomach'. As someone who is afraid of vomiting, I decided to research it and let me tell you... these reviews TERRIFIED me. However, I can say that this medication was (mostly) okay! I was taking it three times a day. Each time I'd take it I'd drink a bottle of water and eat a piece of toast. They recommend not to lay down for 10 minutes after taking it-- wait longer. I attempted to lay down after 20 minutes and had the worst burning in my esophagus ever and that's coming from someone with GERD who is no newbie when it comes to heartburn. I waited 45 minutes to an hour after that and had no issues until the last day. At the end my script I began breaking out in hives, then had the worst heartburn I could ever imagine anytime I tried to lay down. While I didn't face the typical stomach issues, the heartburn was enough to make me wary to ever take this medication again.”

5 / 10
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Rose Alee August 4, 2015

“I took this last year for a severe bacterial infection on my chin last year. It certainly did it's job with clearing up the infection. HOWEVER, I will NEVER be taking this medication again if something similar happens in the future. The side effects I experienced were absolutely excruciating! I had heartburn that made me feel like I was going to die- a sharp pain that felt like a lump in my chest that was stabbing me from the inside. My family thought that I was just being dramatic, but after reading some reviews on here, I know a lot of people have had similar experiences. I took the drug 4x a day, and ended up gaining weight on it, because the only thing that helped dull the pain was eating a TON of food with it.”

5 / 10
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ATBx September 12, 2013

“It works fine for me. It squashed cellulitis of the face. My doctor says it was most likely an MRSA bacteria and that most infections of this type are these days. Side effects are mild diarrhea, some abdominal pain, and unnatural taste in mouth for about 2 hours after taking. The taste is not repulsive to me; it is easily tolerated.”

9 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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