Brexpiprazole and Tiredness: What Users Say (Page 2)

• Not...
• Taken for less than 1 month
• April 24, 2022

Brexpiprazole "I was put on this for Bipolar 2. Within a week of starting, I noticed my eyes starting to “jump” left to right when I tried to focus on things in my hands. And I also seemed to struggle to maintain focus on things or people in front of me as well. Got worse as I kept taking the pills, then gradually went away over the course of a week after I stopped. It also made me super tired to where I wasn’t even hearing my alarm clock in the morning or was putting it on snooze without even remembering I woke up to snooze it. Rexulti isn’t for me. I went right back on Lexapro and Trileptal. The jumpy eyes thing was absolutely intolerable."

• Rex...
• Taken for less than 1 month
• May 13, 2023

Brexpiprazole for Depression "I’m using 0.25 mg and on my third day. It makes you feel tired, and so far I haven’t felt any of the good parts. My mood hasn’t improved. I’m using it alongside Concerta to treat ADHD, and when Concerta wears off, I cognitively don’t feel really sharp. It hasn’t given me major side effects, but I’m not sure if it’s working."

• Tan...
• Taken for less than 1 month
• July 30, 2018

"Used as a mood stabilizer. After 3 days of being on Rexulti, used in conjunction with my Lamictal, I will be stopping immediately. Gave me insomnia, tired throughout the day, restless legs during the night, and completely messed with my libido. Not only does my insurance not cover this medication, it's most definitely not for me."

• May...
• Taken for 1 to 6 months
• July 26, 2025

Brexpiprazole for Depression "With my dissociation, it caused a really blurry existence for 2 weeks when I started it. After that, suddenly felt like for the first time in my medical history of 20+ different medication tries that finally something works. Then after 2 or 3 weeks of feeling really good, I became tired again, which was a common side effect of a lot of medications I have used before. (I have no idea which part of medications makes me tired, but almost all medications make me tired.) Now I started taking the Rexulti at night. It works really well again, and I'm feeling good, and it makes me sleep at night better in consideration it's better like this. Only was put as a morning medicine because I usually forget to take things at night. It worked magic for me. Doctors should say it may cause a blurry existence because when you experience it, you don't have enough awareness to realize you just see nothing happening, and it's over. (I take other meds too, like Scippa with it. I don't think it does anything, but maybe it helps.)"

• Pla...
• Taken for 6 months to 1 year
• February 10, 2017

Brexpiprazole for Major Depressive Disorder "Have been dealing on a daily basis with chronic low-grade anxiety and lethargy/tiredness."

• Pla...
• Taken for 6 months to 1 year
• February 10, 2017

Brexpiprazole for Major Depressive Disorder "Have been dealing on a daily basis with chronic low-grade anxiety and lethargy/tiredness."

• Ano...
• Taken for 1 to 6 months
• April 22, 2025

Brexpiprazole for Agitation Associated with Dementia Due to Alzheimer’s Disease "It is given at night, which causes insomnia when one walks. Then is tired during the day. Is also given buspirone, 5 mg and mirtazapine 15 mg in the morning."

• Ano...
• Taken for less than 1 month
• September 4, 2025

Brexpiprazole for Depression "Haven’t noticed much help with my depression yet, and I've been taking it for several weeks. Definitely makes me really tired, which I don’t like. I’m currently taking 2 mg per day."