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User Reviews for Onexton to treat Acne

Onexton has an average rating of 8.6 out of 10 from a total of 31 ratings for the treatment of Acne. 90% of those users who reviewed Onexton reported a positive effect, while 10% reported a negative effect.

Onexton Rating Summary

8.6/10 average rating

31 ratings from 29 user reviews.

Compare all 321 medications used in the treatment of Acne.

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Reviews for Onexton

Aibeee · Taken for 1 to 6 months June 30, 2020

“This topical acne treatment worked wonders! If you just started or have been using for a couple weeks KEEP USING IT!! I have had problems with acne for 6 years until I used this product. I’ve been on accutane and many other oral and topical treatments and this by far works the best. I started seeing improvement within 2 weeks of using it and since then I’ve gotten very minimal breakouts! The longer you use it the more effective it is for sure! This is also one of the only topicals that doesn’t dry out my skin and make it all flakey. I put on moisturizer before I use this product and my skin never dries out. I’ve never reviewed anything ever but I’m so thankful for this product so I thought I’d share with you all! Don’t give up keep using it! Wish all the best with this medicine!”

10 / 10
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Beau · Taken for less than 1 month May 18, 2020

“Absolutely amazing! Highly recommended for adult/hormonal acne”

10 / 10
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Miracle worker · Taken for less than 1 month February 12, 2020

“Have battled acne since my teenage years. Birth control helped some (it was never perfect even on birth control) but I recently went off birth control and my acne really flared up. My dermatologist prescribed this and within the first week I had clear, smooth skin. I've been using it once a day for about 3 weeks now and my skin hasn't looked this good since I was a kid. A true miracle worker for my skin.”

10 / 10
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NCLE March 16, 2017

“I have struggled with moderate to severe acne since high school (now 24) and have tried just about every product on the market including two rounds of accutane. Last week, I saw my Derm and she put me on Onexton, as well as Retin-A. After less than a week of being on this combination my skin looks better than it has in months and I'm certain it is primarily due to Onexton. Fair warning- the first few days of this medication are very, very rough. I looked like a burn victim and my entire face was peeling, red and burning. However, by about day 4 or 5 it had appeared as though I had gotten a chemical peel and my skin was glowing! Im so, so happy with this medication and have been recommending it to everyone I know.”

10 / 10
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Vanessa_35 May 21, 2015

“Onexton is absolutely amazing! Have been using now for about 3-4 months. I apply it every night after removing my make up and washing my face thoroughly with CeraVe Foaming Facial Cleanser. I was worried about facial skin peeling/redness that I experienced with other prescription topical medications that I had tried in the past for acne (Ex. tretinoin, benzaclin, etc.) I have not had any redness or peeling since starting Onexton. My face is pretty much clear (exceptionally noticeable difference compared to 4 months ago). I also take Spironolactone 100mg daily for acne which was started at the same time as the Onexton. For the first time in YEARS, my face is mostly clear without any redness or peeling. $0 copay with savings card!”

10 / 10
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Dannyeduar September 8, 2016

“I've been on this for a week and half and it's working fine I guess, too early to tell. However it really burns my skin... I guess I have sensitive skin.. Idk but it burns a lot and it's really irritating. I use this with retin a so idk if together they burn but it burns a lot.”

8 / 10
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Km84 · Taken for 6 months to 1 year March 18, 2016

“Onexton was my last resort before Accutane and I am SO glad my derm prescribed it to me. I had hormonal cysts that were painful and inflamed. I've been on Onexton for six months and now I have no acne at all. I feel like I tried everything and this was the only thing that worked for me. Your skin does need time to adjust to it because it's a powerful medication, so make sure you're only using a small amount at first. I like to mix mine with moisturizer and apply at the same time. Seriously has been a lifesaver.”

10 / 10
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sunshynem2 · Taken for 2 to 5 years February 7, 2020

“I've been using Onexton on my acne for 4 years with success. I use it before I go to bed at night, and also wear it under my makeup during the day (it's better than generic because it doesn't cake). I used to get horrible, painful cystic acne before I started it. I'm 95% clear now with an occasional spot or two around my period. The overall texture of my face looks way smoother too. Despite some reviews, I do not find it drying at all. (I also apply prescription tretinoin every couple of days, which does dry me out). My confidence has gone way up since starting Onexton.”

9 / 10
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Jody1288 October 25, 2015

“Amazing! Currently on doxy and onexton. To keep this short I will say I've been on tons of other creams and gels and even accutane twice and nothing has worked this quick for me. My current combo has significantly flatted out my spots in a week. I am still getting a few new ones but I dab some onexton on there and bam. Within 24hrs those pesky spots either shrink or come to a head. I usually have to wait weeks for those under skin ones to go away but this stuff clears them up in a day or so. Yesterday morning I felt a new spot coming up and by nighttime it was gone. Crazy!”

10 / 10
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hayyquayy November 12, 2015

“I am 22 years old and in the last couple of years my skin has gone through some changes. I have oily/combo skin and acne prone. I went to the dermatologist hoping for a simple fix product as I was only trying to control small breakouts. I did not go in with terrible acne, maybe like 3 active pimples. He prescribed Onexton and Epiduo. Told me to use Epiduo at night and Onexton during the day. I had to stop using Epiduo after one week because it was so terribly drying it was changing my skin color. I continued Onexton and my skin got so much WORSE. I continued using for 3 weeks and decided to stop because my breakouts were out of control. I've never had skin this bad before. Switching to an all-natural routine. Fingers crossed.”

1 / 10
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esaxon26 · Taken for 6 months to 1 year February 14, 2019

“This stuff is the BEST! I have suffered with acne for years. Really painful under the skin cystic acne that has literally brought my near tears it hurt so bad. I tried everything and nothing ever worked. This was the last option I had to try before my dermatologist went forward with cortisone shots and Accutane as a last resort. I have been using Onexton once a day for 6 months now and I haven't had a cystic pimple in about 5 months! Or any pimple for that matter besides the one occasional tiny pimple that you can't see and hardly anything comes out. Gone by morning with Onexton! My skin is so clear and smooth I love it. The only 2 downsides is the first month, it made me break out a little more than usual as it was trying to get rid of the acne rather than maintain a clear face like now. The other downside is it does make you dry but as long as you exfoliate once or twice a month and use a good moisturizer you should be square. I am so happy my dermatologist had me try this!”

10 / 10
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Nikita · Taken for less than 1 month August 16, 2019

“I have suffered from moderate acne after going off birth control which messed up my hormonal balance. I have tried countless over the counter creams/masks including retinoids treatments that cause severe dryness with eczema patches. This is the only medication that doesn’t cause any noticeable side effects with noticeable results within a week! The number one complaint I see is dryness which can be completely solved by applying a generous amount of cream like CeraVe right after application.”

9 / 10
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llauramccormick · Taken for 1 to 6 months August 29, 2015

“I've had horrible acne since 4th grade (now in 11th grade) and was also extremely self conscious, since I was way before my peers. My doctor put me on Accutane and it worked wonders. My skin was completely cleared and I was thrilled. After a few months off of it I began to notice some new pimples, so I contacted my dermatologist. She put me on Onexton. Within 2 days the pimples I had were completely gone. I have been putting it on ever since and have had no problems. I would recommend using it with a moisturizer. HIGHLY RECOMMEND”

10 / 10
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JDY2015 October 16, 2015

“I have been fighting cystic acne for years and finally decided to see a dermatologist who prescribed Onexton. It took about two weeks and my cystic acne has cleared completely. I'm also taking Doryx daily. I had no issues with irritation from using the cream daily. I use coconut oil as a moisturizer which seems to work well. I've been using a mineral SPF since all the other cream sunblocks seem to cause breakouts.”

10 / 10
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anonymoususer187 · Taken for 6 months to 1 year October 5, 2018

“I switched my birth control and started getting some break outs so I started using onexton. It cleared my skin pretty fast, but it just makes my skin super dry and irritated that I have to use super heavy moisturizers. Other than that, it’s effective in preventing breakouts and getting rid of acne”

9 / 10
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IT SUCKS · Taken for less than 1 month December 5, 2015

“If I could give this a negative number I would. It murdered my skin. It made my skin horribly worse. I woke up the morning after my first application (which happened to be the day I was taking the SAT!) with my skin just a horrible peeling, painful mess. My skin felt like there was acid under earth it. My face was disgusting, it was completely tight (it looked leathery!!!) and covered with dead skin, I couldn't see fresh skin ANYWHERE. It was all peeling off. And burning. I, of course, stopped using it. But for the next 2 weeks my skin was peeling non stop (moisturizer and exfoliating were no help) and my face was dark red. It looked like I had had an absolutely horrible sunburn. This was after just using Onexton ONCE. Wouldn't recommend.”

1 / 10
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Joann1969 June 25, 2017

“My son started having bad acne when he turned 16. I bought tons of "acne treatments" that you can buy in stores, online from Paula's Choice, Clinique, and even tried Proactive, nothing worked and most made it worse. I felt horrible for him & finally said enough of the rubbish products and took him to the dermatologist who gave him a dermabrasion treatment & a prescription for Onexton. There are even cards that cover most of the cost even if you have insurance. They say 1 bottle/month but it lasts 6 months. My son's face began to clear up within 2 weeks! He is now 19 & hasn't had a break out since he started using Onexton. I am so thankful for this product! Don't waste money and precious time with your child's life, go straight to a dermatologist!”

10 / 10
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S26 June 24, 2016

“My face was breaking out so badly that I didn't even want to look in the mirror, blAvk heads horrible cysts I tried using a homemade mixture for my face which did nothing. My doctor later prescribed onexton and ziana gel onexton in the morning ziana at night I had no idea that after applying the onexton and the ziana to moisturize my skin, So after two weeks of use my skin was red peeling n painful, so I decided to stop using it for a week and get m skin hydrated, than I went back to using the products, I've been using it for about 3 months now and it's cleared all the acne away and all the excess dead skin is gradually coming off. It takes time to see a major difference but I seen my difference within 1 1/2 months . I would recommend both.”

9 / 10
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Anonymous August 26, 2015

“I am 22 years I was given a sample of onexton from my dermatologist so I could get started until I got mine mailed to me. Let me just say this stuff is AMAZING! My breakouts were significantly smaller and less noticeable with the first application. After a week my face was close to completely clear to where I just used it about twice a week. The reason I'm giving it a 9 and not a 10 is because it did dry me out a bit but nothing you can't control with a good moisturizer. Over all in LOVE with this stuff.”

9 / 10
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Angry April 28, 2019

“I spent over $100 for Onexxton to completely destroy my skin. Do not use this if you have sensitive skin. It made my skin so dry and sensitive that I caused more breakouts. I have disfiguring scars from the cystic pimples that Onexton caused. I stopped using this six months ago and my pores are still large, my skin is red, and since my skin is so sensitive I constantly have breakouts that I can’t do anything to prevent since topicals could cause further damage. This is definitely one of my worst decisions.”

1 / 10
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Chris0107 · Taken for less than 1 month May 21, 2018

“I had been suddenly breaking out like crazy. Some huge cystic bumps and everything. I was using aczone and it worked pretty good in the past, but wasn't really helping with this. Was waking up with new bumps every day even with the aczone on overnight. I started onexton and it's been about 2 weeks now. I have not had one new zit appear since starting this medication. All the pimples I had are gone. So I'd say this has been a miracle for me. Only negative Is it can be drying. That seems to be subsiding and a good moisturizer helps.”

9 / 10
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J.I.L. · Taken for less than 1 month July 18, 2015

“I have been dealing with adult acne for years. The product does work but I had to give it a little time. It's been close to a month and my skin is almost clear. I did have a few breakouts last week but were gone 2 days later. I also experienced some dryness and peeling after washing my face with Proactiv and applying onexton right after. The other thing I noticed was unbearable stomach and leg cramps the first day of my period. I usually get cramps but 1 Tylenol normally does the trick; not this time. My cheeks are a little rosier than normal and my chin, which is where I apply most of the medicine, is turning a bit yellow (weird). I think it's worth a shot but get in tune with your body in case there are any side effects”

9 / 10
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Shelby · Taken for 1 to 6 months June 7, 2019

“I love this product Onexton. Disclaimer, it can cause dryness so I apply a facial moisturizer first for sensitive skin. I’ve struggled with acne since puberty and I am now 27 and have clear skin. I’ve tried so many products throughout the years and this one works so well. I got a retail coupon with my derm so it costs $65 but you only need to apply a small amount of gel and it goes so far. I would definitely recommend this medication.”

8 / 10
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ED1997 August 9, 2017

“I have never had a problem with acne until I got into college. I am 20 years old and my acne got so out of control I would never be seen leaving the house without tons of make up covering my blemishes. I tried almost every over the counter acne treatment on the market and didn't notice any difference. Some of them would make a few pimples go away and I would just get them back a couple of days later. I went to the dermotologist and she prescribed me Onexton. This stuff is a miracle! After only using it for one night, I already noticed a significant difference in my face. I've been using it for a week now and my face is almost 100% flawless. It will make ur face dry so make sure to keep moisturizing.”

10 / 10
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Morganatic February 2, 2018

“If I could give this a negative I would. After ONE use my skin was so tight and dry and looked as if I had leather for skin. My face became bright red like a sunburn. At first I thought I was having an allergic reaction and the leathery feeling was hives so I took Benadryl. Nothing changed. I’m on day 3 and still have awful skin. I only used it once and I want my money back. This is the worst skin cleanser I have ever used and advise anyone to use over the counter face wash instead”

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DM January 19, 2019

“I stopped taking my birth control & I began to experience severe cystic acne. I tried everything from over the counter acne treatments, to prescriptions, to home remedies/masks. NOTHING worked. I figured I’d give the dermatologist another try when she recommended Onexton Gel 1.2-3.75%. I immediately noticed a change in skin & my break outs completely stopped. I’ve been on this medication for about 6 weeks & I’ve gotten one small pimple on my cheek that went away within 3 days. The only thing I will criticize is that it can leave your skin dry, but this is nothing a little moisturizer can’t fix. I would most DEFINITELY recommend this medication to those struggling with cystic, inflammatory & harmonal acne. I can truly say it’s been the only acne medication that has worked for me & has made me so much happier!”

9 / 10
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acnenomore · Taken for less than 1 month June 27, 2016

“I was on accutane for 7 months? Something like that. And had no acne at all afterwards but 6 months later I had a random terrible flare up and used onexton, worked pretty well except I put too much on one area so if kinda burnt my skin.”

9 / 10
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Justintb83 · Taken for 1 to 2 years August 2, 2017

“The stuff is amazing! Dissecting cellulitis is just about one of the worst forms of acne that anyone could have. At the first sign of a pimple I put it on and it's gone within a day or two. It's not quite as effective for the dissecting cellulitis but it does help control flareups. Dissecting cellulitis is normally controlled with a steroid and anabiotic's. In my opinion for a topical cream to eliminate the need for steroids and anabiotic's is amazing!”

10 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

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