Bazedoxifene / conjugated estrogens and Joint Pain: What Users Say

• Tre...
• Taken for 1 to 6 months
• June 25, 2019

Bazedoxifene / conjugated estrogens for Hot Flashes "This helped tremendously with the hot flashes, and it kicked in immediately. However, after 4 weeks on this, my ankles are now cankles, and I'm holding water all over, which in turn is causing a ton of joint pain. I was always fairly athletic, and edema was never an issue for me until I began taking Duavee. I'm going to see if the doctor can do anything to counter this swelling. If not, I'll have to go off of them because this is like third-trimester pregnancy swelling, which I just can't handle. Has me sore and achy all over, and I'm blown up like a balloon."

• Eat...
• Taken for 1 to 6 months
• December 21, 2019

Bazedoxifene / conjugated estrogens for Hot Flashes "I'm 55, perimenopausal, and my biggest complaint has been hot flashes. I've been on Duavive (Canada) for 6 weeks, and I've been feeling so much better in so many ways, BUT I will likely have to go off it because I've had a terrible flare-up of IBS. I don't blame Duavive in particular, I blame sex hormone supplementation in general, as this happened 2 years ago while taking progesterone capsules and estrogen face cream (both bioidentical from a compounding pharmacy). I took a one-year break from HRT, but my hot flashes and aching joints forced me to try again. I just wanted to mention this, as some women develop IBS, as it can be a symptom of peri and post-menopause, and taking hormones, for some, makes it worse."

• GCr...
• Taken for 2 to 5 years
• August 6, 2020

Bazedoxifene / conjugated estrogens for Postmenopausal Symptoms "I started taking Duavee about 5 years ago for menstrual periods. After my period stopped, I decided to stop Duavee. Then in May 2018, my doctor put me on Duavee again due to hormone issues. The pill started causing joint pain around my hips and neck pain and muscle spasms, to the point that it caused bulged disc/spine problems. I stopped the pill, but the damage it has done."

• Anonymous
• Taken for 2 to 5 years
• October 23, 2020

Bazedoxifene / conjugated estrogens for Postmenopausal Symptoms "I have taken Duavee for two years. It was great for hot flashes and mood swings. However, I had bloating and weight gain. I have also developed neck pain, joint and muscle pain. I already had pain in my back and hip, but now it’s worse. I have been off Duavee for two months now. Hot flashes and mood swings aren’t as bad now, but my pain is still hanging around."

• M-B...
• Taken for 1 to 6 months
• May 21, 2024

For Hot Flashes "The first week I was sleeping 5 hours without waking. Have not slept more than 1 1/2 consecutive hours in years. The hot flashes decreased the first week, had 2 mild episodes the 3rd week and 1 bad episode week 4. My hot flashes would begin at 8:30 pm accompanied by nausea and dizziness and lasting most of every single night. Since being on conjugated estrogen, my bladder is no longer acting out, burning mouth syndrome is 95% gone, my joint pain is gone, leg pain mostly gone, my libido is returning and lady areas are lubricating again. Mood is improved. My situation is tricky as the doctor also found a thyroid issue, and dealing with that level is harder than the perimenopausal symptoms. Yes, I would recommend Duavive."