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Adapalene topical and Pain: What Users Say (Page 2)

Brand names: Differin, Plixda

Reviews for Adapalene topical

Commonly mentioned side effects
  • Mad...
  • December 17, 2020

Adapalene topical for Acne "I started using Differin 4 years ago, and my skin is definitely completely adjusted by now. It helped me get rid of the small bumps and pimples all over my forehead, chin, and cheeks. The first couple of months that I used it, my skin was very dry and painful, and I had many large cysts come to the surface before disappearing. Four years later, I still use Differin every night, and I get breakouts every month in sync with my menstrual cycle, but it definitely helps get rid of the pimples I do have very quickly, and in general, my acne was helped a lot by Differin, especially considering my bacne is still where it was 4 years ago and my face acne has improved a lot with the use of Differin. I do wish my acne problem was solved completely, but I would much rather just keep using Differin and have occasional breakouts than go on Accutane and maybe never have acne again. I would recommend it if your acne is moderate to severe, but you must have patience for it to do its thing."

8 / 10
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  • Tex...
  • Taken for 1 to 6 months
  • October 12, 2018

For Acne "Tried using Differin gel 2 different times. The first time, I broke out in bad, cystic acne after 2 weeks. Assuming this was a 'purge period,' I kept using the gel a few more weeks. I had to stop due to painful, unsightly cysts on my face. Yes, I followed the directions and tried to be patient. When I stopped using the gel, my skin began to clear a bit. I attempted using the gel again and experienced the same painful cysts on my face. For me, Differin does not work."

2 / 10
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  • fla...
  • Taken for less than 1 month
  • June 30, 2024

Adapalene topical for Acne "So I'm a teenager with mild/moderate acne, and I decided to give Differin a try since benzoyl peroxide and other treatments weren't helping anymore. I followed every step, watched numerous reviews, and started using it. Let me tell you, my skin immediately went berserk. On the second day, I had deep red burns, peeling, and my eyelids were crusting and hurt so much. Moisturizers didn't help and just burned (yes I used gentle ones). It got so bad I threw it away and put Vaseline all over my face. The next day my skin was healing, and the burns were getting better. Do not use this product unless you know what you're doing!"

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 28, 2015

For Acne "After changing my pill after being on the same one for 10 years, I broke out in terrible acne. I had never had bad skin when I was growing up, and I have become so self-conscious. I have only been using Adapalene for two weeks. After reading so many reviews, I was prepared to go through a really bad phase before any improvement. In these first days, I broke out worse than ever in my life, but it felt like Adapalene was pushing dirt out of my pores that had been stuck in there forever. Right now, my chin and jawline are very sore and flaky, I have been moisturizing as much as possible, but even this is irritating the skin. I am pushing through because I really think I am starting to see a change already!"

8 / 10
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  • dai...
  • August 4, 2021

For Acne "I got acne due to coming off the pill. I was put on lymecycline for 9 months, which when I spoke to a professional, said that I should've only been put on for 3-4 months max. After 9 months, I saw that my acne gradually got worse again, so I was prescribed adapalene and doxycycline. Every day I've taken doxy and every night applied adapalene with a moisturizer (I have sensitive skin), but it didn't stop the purge, which I was very aware of happening. It was itchy, painful, and not nice to look at from weeks 2-8, but now I'm going into week ten and it's less bumpy, less irritation, and definitely less spots appearing. All that's left is to fade pigmentation, which I knew would happen. I'm overall happy with the progress of my skin as it hasn't been a linear experience with my skin, but now I feel it going back to normal."

9 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • September 6, 2021

Adapalene topical for Acne "I have been using Differin for 6 months. The purge lasted 1 month and a bit super sore as I was working outside every day. After that, skin would start to clear, but I would always have 5 pimples or cysts and irritated skin. Skin never fully cleared. And if it did, it lasted for one day, then I got more pimples. I recently changed how I apply at night, and it started to clear and be less irritated. *Wash CeraVe Hydrating Cleanser *Neutrogena Hydro Boost Moisturizer (while skin is wet) *Niacinamide 10%. ('let dry) *Neutrogena Hydro Boost (let dry) *Differin (wait 20 min) *Moisturize CeraVe Dry Skin."

5 / 10
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  • Sam...
  • September 22, 2015

Adapalene topical for Acne "A dermatologist (a different dermatologist than I usually see) recommended starting to use Differin along with taking my Doxycycline. I have been using the topical gel for 3 days on my face and back, and I only have negative things to say. My face is peeling badly, and the skin is very red and irritated. I have tried different moisturizers, and they just burn. The outer corners of my eyes are red and painful. My back broke out with large blister-like pimples. I do not have sensitive skin, and my acne is not very bad. I feel this product has actually worsened my condition. I am going to stop using Differin immediately. I don't know how long it's going to take my skin to heal."

1 / 10
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  • Ken...
  • Taken for less than 1 month
  • March 20, 2019

For Acne "The retinization period is bananas! I started this treatment Friday, March 15, and stopped using it March 17! The side effects, and I have every one of them, are painful!!!! The one time I didn't Google the medication before I used it! My chest is on fire, and it looks horrible! I only pray these side effects go away quickly! I read to continue using this medication even with the side effects! My chest burns just thinking about that! This is so embarrassing! I love my chest, and to see it all broken out, red, and burning is so discouraging! Good luck to whomever uses this medication! Just believe the side effects are real!!"

3 / 10
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  • ano...
  • Taken for less than 1 month
  • April 15, 2019

Adapalene topical for Acne "The first 2 weeks while using Differin, my skin seemed to clear up and didn't break out as much. However, when the 3rd week of me using this treatment commenced, I woke up with leathery skin and flaky skin on my upper lip area below my lip and on the side of my lip (basically my mouth area). I'm in so much pain, and I look horrible and feel horrible. I've never cried so much in my life. DO NOT buy this!"

3 / 10
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  • Em2...
  • November 10, 2017

Adapalene topical for Acne "I used this one time before sleeping. I put on moisturizer about five times the next day, and my face still hurt. Today is the second day after using this product, and my face still hurts, is red, and is puffy after applying moisturizer another five times today. I don't think it's supposed to hurt this bad, even if there is a purging process. I would not recommend this product."

1 / 10
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  • Ash...
  • Taken for less than 1 month
  • January 9, 2020

Adapalene topical for Acne "Starting from age 15 till now age 33 I’ve fought the good fight against acne. Nothing worked. I saw a dermatologist and was prescribed Differin gel. The first four applications or so, all good. After that, peeling and pain. I thought about pushing on, but I decided clear skin wasn’t worth that much pain. I stopped using it after 6 applications, but it took a few weeks for the pain and peeling to stop. After that, I suddenly had terrible acne. I had it in places I had never had it before. My face was covered. After a couple of months, my face returned to semi-normal acne levels. I decided to try to treat the acne at its source, so I got a small tube of benzoyl peroxide and applied it. It was like a miracle cure. Overnight I had clear skin for the first time in years. I use it every few days. I recommend it to anyone suffering like I was!"

1 / 10
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  • cmf...
  • Taken for less than 1 month
  • February 15, 2017

Adapalene topical for Acne "(A little background on my skin, I get a pimple here and there and overall have pretty normal skin.) I saw a commercial for Differin and immediately went online to buy it. I thought that the product sounded great for the price! After I purchased it, I started looking into side effects and reviews on the product. They were pretty mixed, with some people saying they loved it and others saying they hated it, but the main thoughts were that it might make your breakouts worse for a few months, then get better, and it can make your skin dry and sensitive. Well, let me tell you I used this product as directed for 3 nights in a row, and it gave me a chemical type burn on my face. My skin is flaking off, and I am using a TON of moisturizer to try to keep it as hydrated as I can, and it hurts to even touch my face. And I don't mean like when your skin is dry type of flaking off, I mean like worse sunburn in your life type of flaking off. I also have a pretty high pain tolerance, and anytime I touched my face, took my makeup off, put makeup on, or used my moisturizer, it felt like 10,000 needles stabbing me in my face while getting burned by a hot iron. I have now stopped using the product, and two days later, my skin is still the same; flaking, red, and hurting like no other. Do NOT use this product unless you are ready for some serious pain and skin damage."

1 / 10
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  • Lea...
  • Taken for less than 1 month
  • September 21, 2019

Adapalene topical for Acne "Used this product for 1 week. During this first week, my face turned red and started burning to the point that rinsing my face was painful. However, it cleared up my acne for a few days, then the breakout started back."

5 / 10
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  • Mor...
  • March 16, 2017

Adapalene topical for Acne "It was freaking horrible. I have a mild case of acne, used this horrible acne gel, and it burned my entire face. I don't even want to walk out of my house! When I step into my car with the heat, it's an excruciating pain that won't go away. I would never recommend this product to anyone! I'm a very beautiful woman, and my self-esteem has dropped dramatically! I cry myself to sleep since using this. I can't believe they really sell this in stores!!!!"

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.