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Acyclovir for Herpes Simplex User Reviews (Page 2)

Brand names: Zovirax, Sitavig

Acyclovir has an average rating of 8.0 out of 10 from a total of 83 reviews for the treatment of Herpes Simplex. 72% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Acyclovir

  • Sadbu...
  • Taken for less than 1 month
  • June 10, 2019

"I became very irritated down there to the point it hurt to go to the bathroom I schedule an appointment for the doctor and they told me I had a yeast infection I then noticed bumps down there and they tested for HSV2 (herpes simplex 2) came back positive. Currently day 3 of acyclovir and I am so happy to almost be back to myself. The pain I went through was unbearable... had to call out of work several times because I could barely walk. We will see how this medicine works for me overtime"

8 / 10
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  • Sloany
  • August 8, 2019

"So I am 65 and haven’t had an outbreak for 4 years. In the past couple of days I’ve had a burning sensation that comes and goes. It’s in a different place than I’ve ever had it. There is absolutely nothing to see, no blisters or sore. But it is so tender I’m lying around with ice on my crotch. My jeans shorts were painful to the area. I have the Acyclovir on hand but how do I know if it’s a herpes outbreak.? It almost feels like it’s bruised. Again nothing visible. Is this a giant outbreak waiting to surface?? Is it harmful to take a corse of it “just to be safe?”"

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  • Still...
  • Taken for 10 years or more
  • December 23, 2016

"Since early childhood I've gotten painful and gross cold sores. Just awful. In my nose sometimes, down my chin...yuck. I hate this virus. I tried all the wacky home remedies...yeah that battery powered silvery piece of rubbish I figured I'd just be Quasimoto every 3 or 4 months and just deal with it. :( Until Acyclovir 800. What IS this stuff?!?! It's magic, that's what it is. YMMV, I personally have to take 4 at first tingle to stop it "cold." It never gets red, never gets to blister. Certainly not that fun cracked, bleeding horror show round about day 6 without this stuff. So to make a long story longer, get Acyclovir 800. An interesting side effect is that I also have fewer, and less severe outbreaks. Thanks for reading,"

10 / 10
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28 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • June 27, 2012

"If you get a cold sore outbreak in your mouth. Don't walk, RUN to the nearest medical practitioner that can give you a prescription of Acyclovir. Usually an outbreak would last me 3 weeks with just using over the counter creams. With the medication, my mouth was back to normal after 4 days."

10 / 10
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39 Report
  • Tamek...
  • Taken for less than 1 month
  • January 12, 2016

"I am 19 years old and I just got diagnosed this 2 days ago. Someone took advantage because I was drunk he began stroking and I jumped up about 2 minutes into it. He was a creep all the way around but that's the only person I've could've got it from and I'm positive about that. Now I can't get in contact with the boy and my life is torn apart. I honestly so upset about this because this pain is so unbearable it hurts, burns, and itches to stand up, sit down, walk, etc. when I urine it burns super bad, and I am in misery. I can't deal with this for the rest of my life. I haven't even been showering because it burns so bad. I just started the meds 400 mg/8 hrs no progress yet though. Any suggestions???"

3 / 10
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30 Report

Are you taking this medicine?

  • suporto
  • February 19, 2016

"I have been taking generic (cheap) acyclovir for 52 years. I am 67 and contracted the herpes simplex while out in the sun at age 15. Consequently, I have not been sunbathing for 52 years and look like I am 50. There have been no side effects and I take this every day--800 mg. When I stop, I get an outbreak. Tried to go off it last year and had 5 outbreaks in 4 months. So now back on. Take it the minute I feel a tingle, 5 a day for 5 days and no problems. But still wear 70 sunscreen."

10 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • September 16, 2015

"I'm 25 years old, When I first realized something was wrong was when I felt like I had a cut down on my genital area, I then realized there was a new form of a bump and then the itching came along and the burning sensation when I used the restroom. I decided to see the clinic because i knew something was wrong. She ran tests which I am still waiting for to come in this week, but from what she said, she said it looks like Herpes. She prescribed me acyclovir 400mg this past Monday which was two days ago. I have to take one ever 12 hours. It seems to work for so long, like a few hours, but i am still feeling the pain, and I feel like more bumps have appeared. I'm terrified. I still have burning sensation. "

6 / 10
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  • ocsun...
  • Taken for less than 1 month
  • December 13, 2012

"I used to get Cold Sores rarely, but more stress & it's been a nightmare! On top of that I kept missing work whenever I got breakouts (for a week at a time) because I'm a Spokemodel. I started to get desperate, because I couldn't be reliable for work & started losing huge amounts of my income. Plus Cold Sores are a major bummer to go through. Finally talked to my Dr. I've been taking only 200mg a day. Then a few days ago, I took a chance and tanned my face & whammo I started getting a breakout. As soon as it came on I dosed up the Acyclovir and iced it for 2hrs. This stopped the sore in it's tracks. It disappeared completely and I am cold sore free! I can't tell you how relieved I am at how well this medicine works!"

10 / 10
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  • Anonymous
  • Taken for 10 years or more
  • July 1, 2017

"I'm 48 and I was diagnosed with genital herpes when I was 35. I started dating a new guy and within 2 weeks I felt horrible burning when I urinated. I went to my midwives and sure enough I had herpes. Funny thing is I wasn't with anyone prior to him and I was with him for 6 years and not once did he ever test positive. They actually claim I could have had it on my face touched it and touched my genitals without washing my hands and transferred it. The outbreaks are less and less over the years but when I feel one coming I take acyclovir 500mg 2x daily. It helps right away. And I use a squirt bottle with warm water as I urinated to help reduce the burning."

10 / 10
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  • HeyLo...
  • Taken for 10 years or more
  • April 8, 2019

"Have had HSV2 for 30 years and take Acyclovir 400 mg for episodic outbreaks. In the "early years",I used Zovirax ointment, which is very good, but the tablets are betteras you take the medication early, before the dreadful outbreak, in the form of Acyclovir 400mg/2-3x daily for 3-5 days has been an unbelievable blessing. It IS a horrible disease, but Acyclovir makes it bearable."

10 / 10
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  • Ohhey...
  • Taken for less than 1 month
  • July 28, 2019

"Stress is NO good for people with HSV2 it activates the virus. I’ve had a rash for about 3 months. Until I got fed up and missed seeing my privates clean and smooth so took a trip to my gyno and she prescribed me acyclovir twice a day and it’s almost clearing up!! On my 5th day of taking the pill."

9 / 10
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16 Report
  • HSVSu...
  • July 1, 2016

"This stuff works great. I had my initial outbreak last year and thankfully had no pain, just itchiness. Got the sores and went to the doc- 800mg 3 times a day for 10 days. Within three days, maybe even two, they completely shrank and i could barely see them. By the 5th day completely gone. Few days ago 3 bumps appeared and I got another RX. On the third day and it is completely gone. Maybe some gastrointestinal discomfort as a side effect but that might have been to my crappy diet the last few days too :)"

10 / 10
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  • jlsAL
  • July 25, 2008

Zovirax (acyclovir) "I have been taking zovirax for over 12 years, 400 mg each night at bedtime. I have only had a few outbreaks, caused by kissing my husband who had outbreaks. On doctor's orders, I am to increase to 800 mg each night at bedtime when I do have an outbreak, or when I'm not feeling well. Other virus' can set off a cold sore attack."

10 / 10
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37 Report
  • Anony...
  • March 29, 2017

"About 5 days ago I realized a cut, I thought I had cut myself while shaving... it then got very uncomfortable and burned while I urinated. Finally, I took my camera down there and wanted to look... I noticed a few more cuts that look like canker sores so I made an appointment right away. She told me it looked like genital herpes. She gave my the cream and the pills. It's only been a day and it doesn't feel like it's working. I know it's soon. But I still feel like I'm on fire, I'm itchy, and it still burns like crazy. Is there anything else I can do?"

2 / 10
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  • Senior...
  • Taken for 10 years or more
  • July 21, 2015

"In my 70's now, thanks to my ex-wife who gave me herpes 10 years ago, I have to take acyclovir every day for past 10 years.. If I don't I will have a breakout if I skip a day. I am most fortunate than others. I get my sores on my lower back only. The outbreaks are rare but are brought on by stress. Wish there was an alternative, but none have been proven to work."

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  • Vanes...
  • February 25, 2015

"Acyclovir 800 tab 4 times a day for 5 days. First pill stopped the cold sore in its tracks it immediately stopped growing with just the first pill. Second day the tingling phase stopped, they erupted, and by the end of the 2nd day they were drying out. I had to stop at the end of day 2 due to this medicine being too strong for my stomach. I ended up with a gastritis flare up, terrible stomach pain, diarrhea and nausea. If it wasn't for that, this medicine would get 10/10!"

6 / 10
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  • Blessed
  • August 19, 2019

"I've been using Acyclovir for some time now. Sadly I am noticing that it takes longer to work when I am having an outbreak and I am also noticing outbreaks in different places I never had them before. My hair is beginning to fall out which I was never told was a side affect. I am stressing even more having to deal with those which is cause more frequent outbreaks."

6 / 10
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  • Krreno
  • Taken for less than 1 month
  • July 16, 2016

Zovirax (acyclovir) "I had a sudden onset of cold sores and a new one was appearing each day. I am on immunosuppressants so my body just can't fight this virus on its own. After 5 days I went to my doctor. This medication was amazing- within 24-48 hrs the blisters were crusting over. The swelling and redness was decreasing as well. I am on 400 mg 3 x daily for 10 days. I am currently on day 6. For the first few days I would feel lightheaded (not dizzy) for a few hours after each dose, but that has gone away now. No nausea when taken with food. I did have a few mild headaches, but that was because I was not drinking enough fluid. As soon as I hydrated, headaches were gone. My doctor gave me 2 refills so next time I feel the onset I can start treatment right aw"

8 / 10
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19 Report
  • Hang...
  • Taken for 2 to 5 years
  • September 5, 2018

"After trying A LOT of different things Acyclovir is definitely what you need to be taking ASAP. As soon as you feel any tingling at all. If you are unfortunate enough to have reached the weeping sores phase I found the only thing to soothe the pain was salt water with black tea. Pop a tea bag in with hot very salty water and cleanse your intimate area once cool enough. Sounds mad but you'll thank me after!"

8 / 10
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15 Report
  • Anonymous
  • December 11, 2011

Zovirax (acyclovir) "Zovirax is my first choice for treatment of cold sores which I've had since I was a young girl. Using it in conjunction with Abreva helps promote healing from within the sores; and eliminates the crusty/scabbing that comes with cold sores. Abreva is best used at the first sign of any itching (that familiar feeling of onset) apply as directed on the bottle, and your cold sore will be gone without anyone noticing you even have one. I am just getting over one and with Abreva alone it took three days, no scabbing or crusty formation making it unsightly and causing embarrassment."

8 / 10
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  • Anonymous
  • November 4, 2011

Zovirax (acyclovir) "I used to have cold sores all the time when I was a child, either when exposed to too much cold or when exposed to too much heat. Finally, I found a doctor who gave me a prescription (just a few years ago, I'm already an adult) and the Doctor prescribed Zovirax 200 mg 5x a day for 5 days. When I am able to take the medicine as soon as I feel the blister forming, the blister will only last for a day; it will grow and then burst and crust over within twenty four hours, so I've never really had to take the medication for more than 2-3 days. Very thankful for this medicine."

10 / 10
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  • Anonymous
  • July 22, 2011

"If you take it right at the start of an outbreak it works really well. The sores that have already formed will disappear in about a week and it will completely stop any other sores from forming after the first dose. The only issue is that it makes me feel really ill. I feel nauseated all day, have diarrhea and completely lose my appetite."

8 / 10
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25 Report
  • SmileA
  • December 1, 2015

"I love this medication. I've always used abreva but decided to get a prescription because abreva took forever to kick in. I recently had an outbreak because of stress at work. It started with one blister. I put the ointment and it went away in 24 hours with a minimal scab. I then had another outbreak 2 days after. This one also went away immediately with a minimal scab. The same weekend I got a bad outbreak where my lip swole up as well. I applied the ointment at night. The next day by 6pm the swelling was gone and the blisters became a tiny scab. I LOVE this ointment."

10 / 10
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18 Report
  • mercy
  • Taken for less than 1 month
  • May 1, 2015

"I have been on this pill now for three days after suffering an attack for almost a week, I am feeling much better. The tingling and itching have reduced. Anti itch medicated cream from the 99 cent store really helped with the itching. I am just a lil tired and feel a little achy. I will take that anytime than the feeling of this painful virus."

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  • TDano
  • July 17, 2009

Zovirax (acyclovir) "Been on Zovirax for 15 years. It barely worked when I started using it for genital outbreaks, absolutely does not work now. Three prescriptions of 800mg x 3 times per day has not slowed down or even put a dent in a 4 month long outbreak."

1 / 10
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26 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Herpes Simplex

Symptoms and treatments

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