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Verzenio and Tiredness: What Users Say

Tiredness: mentioned by 5 users (16.1%)

Based on user experiences from 31 Verzenio reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 35.5%
fatigue 19.4%
tiredness 16.1%

Reviews for Verzenio

Commonly mentioned side effects
  • Swi...
  • Taken for 1 to 2 years
  • May 21, 2023

For Breast Cancer "I’ve been taking Verzenio for just over 1.5 years and have about 5 months to go. I'm taking it because I’m at high risk for recurrence. I take 150 mg twice daily. I have diarrhea just about every day, often multiple times per day. Imodium helps, but I have to take that sparingly or I will have the opposite problem. I am exhausted all the time and have very low energy. I have terrible GERD also, but Pepcid has really helped that. I will finish this medication because I’ll do anything to have as much time as possible with my family. I feel the side effects are worth the potential benefits."

7 / 10
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68 Report
  • Gir...
  • Taken for 1 to 6 months
  • January 26, 2025

For Breast Cancer "Very helpful after lowering the dose from 150 to 100. Was more bearable with side effects. Cancer tumors shrank dramatically. I feel a lot better, still kinda tired on some days, but very tolerable. I don't vomit anymore and less going to the restroom."

10 / 10
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8 Report
  • C H...
  • Taken for 1 to 6 months
  • May 21, 2023

For Breast Cancer "Started on Verzenio. At first, I had diarrhea when eating milk products, including small amounts of dairy in any foods. This was at 150 mg twice daily. The diarrhea got worse and would not stop no matter what I ate. It slowed to a stop when I went on the 100 mg. My lungs have a bit of a problem, my creatinine levels are a bit high, and my white count is down. I am tired and need 1-2 naps a day. But I am managing. I am back to work 1-3 days a week. Loving my job. I found Gatorade and Powerade to help along with my vitamins."

7 / 10
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36 Report

Frequently asked questions

  • Tyl...
  • Taken for 1 to 2 years
  • August 26, 2024

For Breast Cancer "I am taking 150 mg twice daily and anastrozole. Both medications were started at the same time. Side effects have been manageable but have included weight gain, tiredness, and minor stomach/digestive issues. I have not had to take any Imodium."

10 / 10
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13 Report
  • Kri...
  • Taken for 1 to 6 months
  • August 5, 2024

For Breast Cancer "Verzenio is the hardest drug I've been on. So many side effects I'm too tired to mention. Reduced to 100 mg, still the exhaustion is the worst side effect. Came off for radiation and felt amazing. Forgot how great I used to feel before this shitty drug."

6 / 10
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11 Report

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