Generic name: Trimipramine [ trye-MI-pra-meen ]
Drug class: Tricyclic antidepressants
Medically reviewed by Drugs.com. Last updated on Dec 27, 2022.
- Drugs like this one have raised the chance of suicidal thoughts or actions in children and young adults. The risk may be greater in people who have had these thoughts or actions in the past. All people who take Surmontil (trimipramine) need to be watched closely. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur.
- This medicine is not approved for use in children. Talk with the doctor.
Uses of Surmontil:
- It is used to treat low mood (depression).
What do I need to tell my doctor BEFORE I take Surmontil?
- If you have an allergy to trimipramine or any other part of Surmontil (trimipramine).
- If you are allergic to Surmontil (trimipramine); any part of Surmontil (trimipramine); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have had a recent heart attack.
- If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen.
- If you are taking any of these drugs: Linezolid or methylene blue.
This is not a list of all drugs or health problems that interact with Surmontil (trimipramine).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Surmontil (trimipramine) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Surmontil?
- Tell all of your health care providers that you take Surmontil (trimipramine). This includes your doctors, nurses, pharmacists, and dentists. This medicine may need to be stopped before certain types of surgery as your doctor has told you. If Surmontil (trimipramine) is stopped, your doctor will tell you when to start taking Surmontil (trimipramine) again after your surgery or procedure.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how Surmontil (trimipramine) affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- If you have been taking Surmontil (trimipramine) for many weeks, talk with your doctor before stopping. You may want to slowly stop Surmontil (trimipramine).
- Talk with your doctor if you have seizures or have ever had seizures.
- If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
- Tell your doctor if you have signs of high or low blood sugar like breath that smells like fruit, dizziness, fast breathing, fast heartbeat, feeling confused, feeling sleepy, feeling weak, flushing, headache, more thirsty or hungry, passing urine more often, shaking, or sweating.
- Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
- Some people may have a higher chance of eye problems with Surmontil (trimipramine). Your doctor may want you to have an eye exam to see if you have a higher chance of these eye problems. Call your doctor right away if you have eye pain, change in eyesight, or swelling or redness in or around the eye.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
- If you are 65 or older, use Surmontil (trimipramine) with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Surmontil (trimipramine) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Surmontil) best taken?
Use Surmontil (trimipramine) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take at bedtime if taking once a day.
- Keep taking Surmontil (trimipramine) as you have been told by your doctor or other health care provider, even if you feel well.
- It may take a few weeks to see the full effect.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you take 1 daily dose at bedtime, do not take the missed dose the next morning.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Chest pain or pressure or a fast heartbeat.
- A heartbeat that does not feel normal.
- Feeling confused.
- Hallucinations (seeing or hearing things that are not there).
- Bad dreams.
- A burning, numbness, or tingling feeling that is not normal.
- Change in balance.
- Very bad constipation.
- Very bad belly pain.
- Fever or chills.
- Sore throat.
- Feeling very tired or weak.
- Ringing in ears.
- Trouble controlling body movements.
- Any unexplained bruising or bleeding.
- Yellow skin or eyes.
- Mouth irritation or mouth sores.
- Change in tongue color.
- Trouble passing urine.
- Hair loss.
- Enlarged breasts.
- Nipple discharge.
- Change in sex interest.
- Not able to get or keep an erection.
- Swelling of the testicles.
- A severe and sometimes deadly problem called serotonin syndrome may happen. The risk may be greater if you also take certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or very bad headache.
What are some other side effects of Surmontil?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Dry mouth.
- Feeling sleepy.
- Upset stomach or throwing up.
- Feeling tired or weak.
- Not hungry.
- Change in taste.
- Stomach cramps.
- Not able to sleep.
- Weight gain or loss.
- Sweating a lot.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Surmontil?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Surmontil (trimipramine) is refilled. If you have any questions about Surmontil (trimipramine), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
More about Surmontil (trimipramine)
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- During pregnancy
- Drug class: tricyclic antidepressants
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