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Pentafluoropropane and Tetrafluoroethane

Generic name: Pentafluoropropane and Tetrafluoroethane [ pen-ta-flure-oh- PRO-pane-& tet-ra-flure-oh-ETH-ane ]
Brand names: Gebauer's Instant Ice, Gebauer's Pain Ease, Gebauer's Spray and Stretch
Drug class: Topical anesthetics

Medically reviewed by Last updated on Oct 26, 2022.

Uses of Pentafluoropropane and Tetrafluoroethane:

  • It is used to ease pain from muscle and sports injuries.

What do I need to tell my doctor BEFORE I take Pentafluoropropane and Tetrafluoroethane?

  • If you have an allergy to pentafluoropropane, tetrafluoroethane, or any other part of pentafluoropropane and tetrafluoroethane.
  • If you are allergic to pentafluoropropane and tetrafluoroethane; any part of pentafluoropropane and tetrafluoroethane; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have any of these health problems: High blood sugar (diabetes) or poor blood flow.

This is not a list of all drugs or health problems that interact with pentafluoropropane and tetrafluoroethane.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take pentafluoropropane and tetrafluoroethane with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Pentafluoropropane and Tetrafluoroethane?

  • Tell all of your health care providers that you take pentafluoropropane and tetrafluoroethane. This includes your doctors, nurses, pharmacists, and dentists.
  • This medicine may cause harm if swallowed. If pentafluoropropane and tetrafluoroethane is swallowed, call a doctor or poison control center right away.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using pentafluoropropane and tetrafluoroethane while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Pentafluoropropane and Tetrafluoroethane) best taken?

Use pentafluoropropane and tetrafluoroethane as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Do not take pentafluoropropane and tetrafluoroethane by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Hold upright about 3 to 7 inches (8 to 18 cm) from the treatment area.
  • Put on affected part only.
  • If using for sports injuries or care, spray hurt part for 4 to 10 seconds until skin begins to turn white. Do not frost the skin.
  • If you are using pentafluoropropane and tetrafluoroethane for muscle tension or spasms, spray affected muscle until skin begins to turn white. Do not frost the skin. Right after putting pentafluoropropane and tetrafluoroethane on, stretch the muscle gently.
  • Do not put pentafluoropropane and tetrafluoroethane on the face.
  • Do not put on open wounds, cuts, or irritated skin.

What do I do if I miss a dose?

  • This medicine is used on an as needed basis. Do not use more often than told by the doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • A burning, numbness, or tingling feeling that is not normal.
  • Irritation where pentafluoropropane and tetrafluoroethane is used.

What are some other side effects of Pentafluoropropane and Tetrafluoroethane?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Change in color of skin.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Pentafluoropropane and Tetrafluoroethane?

  • Store at room temperature.
  • Protect from heat or open flame. Do not puncture or burn even if it seems empty.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about pentafluoropropane and tetrafluoroethane, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

More about pentafluoropropane / tetrafluoroethane topical

Patient resources

Other brands

Gebauer's Spray and Stretch

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.