Generic Name: naratriptan (NAR-a-TRIP-tan)
Brand Name: Amerge
Naratriptan is used for:
Relieving certain types of migraine headaches. It may also be used for other conditions as determined by your doctor.
Naratriptan is a serotonin 5-HT1 receptor agonist. It works by narrowing blood vessels in the brain.
Do NOT use naratriptan if:
- you are allergic to any ingredient in naratriptan
- you have a history of hemiplegic or basilar type migraine headache
- you have severe liver or kidney problems, or uncontrolled high blood pressure
- you have certain types of irregular heartbeat (eg, Wolff-Parkinson-White syndrome)
- you have a history of heart problems (eg, coronary artery disease, heart attack), blood vessel problems (eg, in the legs, arms, stomach, kidney), chest pain (eg, angina), stroke or transient ischemic attacks (TIA), or blood circulation problems
- you have taken another 5-HT1 receptor agonist (eg, sumatriptan), an ergot-type medicine (eg, dihydroergotamine), or methylsergide in the past 24 hours
Contact your doctor or health care provider right away if any of these apply to you.
Before using naratriptan:
Some medical conditions may interact with naratriptan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a family member with a history of coronary artery disease or heart disease
- if you have diabetes, liver or kidney problems, or fast or irregular heartbeat
- if you have a history of high blood pressure, high cholesterol, shortness of breath, unusual growths in the brain, or other types of headache (eg, cluster headache)
- if you smoke or are very overweight
- if you are female and are past menopause or have had a hysterectomy
- if you are a male older than 40 years old
Some MEDICINES MAY INTERACT with naratriptan. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), selective serotonin reuptake inhibitors (SSRIs) (eg, citalopram, fluoxetine), serotonin 5-HT1 receptor agonists (eg, sumatriptan), serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine, venlafaxine), sibutramine, tricyclic antidepressants (eg, amitriptyline), or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur
- Ergot alkaloids (eg, ergotamine), hormonal contraceptives (eg, birth control pill), or methylsergide because they may increase the risk of naratriptan's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if naratriptan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use naratriptan:
Use naratriptan as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with naratriptan. Talk to your pharmacist if you have questions about this information.
- Take naratriptan by mouth with or without food.
- It is best to take a dose of naratriptan as soon as you notice headache symptoms of a migraine attack.
- If your headache returns or you do not get full relief after one dose, you may take another dose at least 4 hours after the first dose.
- If you do not get any relief from the first dose, do not take additional doses without first checking with your doctor.
- If you miss a dose of naratriptan and you still have a headache, take it as soon as possible. Do not take 2 doses at once. Do not take more than 2 doses in a 24-hour period.
Ask your health care provider any questions you may have about how to use naratriptan.
Important safety information:
- Naratriptan may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use naratriptan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Naratriptan should not be used to prevent or reduce the number of migraine headaches you have. If you have a headache that is different from your usual migraine attacks, check with your doctor before using naratriptan.
- Overuse of naratriptan may cause your headache to become worse. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Rarely, serious heart problems (eg, heart attack, irregular heartbeat) have been reported within a few hours of using naratriptan. Contact your doctor at once if fast or irregular heartbeat; chest, jaw, or neck pain or numbness; sudden, severe nausea or vomiting; sudden, unusual sweating or weakness; shortness of breath; fainting; or vision changes occur. Discuss any questions or concerns with your doctor.
- Serotonin syndrome is a possibly fatal syndrome that can be caused by naratriptan. Your risk may be greater if you take naratriptan with certain other medicines (eg, SSRIs, MAOIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
- Lab tests, including blood pressure, heart function, and kidney or liver function, may be performed while you use naratriptan. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Naratriptan should not be used in the ELDERLY; the risk for serious side effects (eg, heart problems, high blood pressure) may be increased.
- Naratriptan should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using naratriptan while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use naratriptan, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of naratriptan:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; drowsiness; flushing; numbness or tingling of the skin; tiredness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the eyelids, mouth, face, lips, or tongue; unusual hoarseness); blood in stool; burning or aching feeling in your feet or toes; chest pain; fast or irregular heartbeat; fever, chills, or sore throat; heaviness or tightness in your leg muscles; mental or mood changes; numbness, tingling, or weakness in the legs; pain, tightness, or pressure in the jaw, throat, neck, or chest; pain or cramps in the legs or hips; severe or persistent constipation or diarrhea; severe or persistent dizziness; sudden, severe, or persistent nausea or stomach pain; shortness of breath; symptoms of a stroke (eg, confusion, one-sided weakness, slurred speech, vision changes); unusual sweating; unusual weight loss; very cold or blue fingers or toes; vision loss; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of naratriptan:
Store naratriptan between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, light, and moisture. Do not store in the bathroom. Keep naratriptan out of the reach of children and away from pets.
- If you have any questions about naratriptan, please talk with your doctor, pharmacist, or other health care provider.
- Naratriptan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take naratriptan or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about naratriptan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to naratriptan. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using naratriptan.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: antimigraine agents
Other brands: Amerge