Skip to Content

Misoprostol

Pronunciation

Generic Name: Misoprostol (mye soe PROST ole)
Brand Name: Cytotec

  • This medicine may cause birth defects, loss of the unborn baby, or premature birth if you take it while you are pregnant. It may also cause the uterus to tear (rupture). The chance of a rupture is raised as you get further along in pregnancy, or if you have had uterine surgery like a C-section in the past. A rupture can lead to very bad bleeding, and your uterus may need to be removed. Sometimes, a rupture has been deadly. If you are taking misoprostol to prevent gastric ulcers, do not take it if you are pregnant.
  • Most of the time, this medicine is not for use in women who are able to get pregnant. However, there may be times when it is used in these women. Talk with the doctor.
  • If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting misoprostol. Talk with your doctor.
  • Use birth control that you can trust to prevent pregnancy while taking this medicine.
  • You may need to have a pregnancy test while taking misoprostol. Talk with your doctor.
  • Start taking this medicine only on the second or third day of your next normal period (menstrual) cycle.
  • If you are pregnant or you get pregnant while taking misoprostol, call your doctor right away.
  • Follow how to use as you have been told by the doctor or read the package insert.
  • Do not share this medicine with others.

Uses of Misoprostol:

  • It is used to prevent NSAID-associated gastric ulcers in patients with a history of ulcers.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Misoprostol?

  • If you have an allergy to misoprostol or any other part of misoprostol.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are getting oxytocin.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take misoprostol with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Misoprostol?

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Misoprostol) best taken?

Use misoprostol as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take this medicine with food.
  • Do not take antacids that have magnesium with misoprostol.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad belly pain.
  • Very loose stools (diarrhea).

What are some other side effects of Misoprostol?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Loose stools (diarrhea).
  • Belly pain.
  • Stomach cramps.
  • Upset stomach.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Misoprostol?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take misoprostol or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to misoprostol. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Hide