Generic Name: Panobinostat (pan oh BIN oh stat)
Brand Name: Farydak
Medically reviewed on Feb 18, 2019
- Diarrhea is common with Farydak (panobinostat) and can be severe. Call your doctor to find out what to do if you have diarrhea or stomach cramps. You will need to take care not to become dehydrated. Do not try to treat diarrhea without first checking with your doctor.
- Very bad and sometimes deadly heart problems like abnormal heartbeats have happened with Farydak (panobinostat). Abnormal heartbeats may happen because of electrolyte problems. Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You will need an ECG before starting Farydak (panobinostat) and during treatment. Talk with your doctor.
Uses of Farydak:
- It is used to treat multiple myeloma.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Farydak?
- If you have an allergy to Farydak (panobinostat) or any part of Farydak (panobinostat).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have an infection.
- If you have liver disease.
- If you have a certain type of chest pain (unstable angina).
- If you have had a recent heart attack.
- If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with Farydak (panobinostat).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Farydak (panobinostat) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Farydak?
- Tell all of your health care providers that you take Farydak (panobinostat). This includes your doctors, nurses, pharmacists, and dentists.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Very bad and sometimes deadly infections have happened in patients who take Farydak (panobinostat). If you have any infection, are taking antibiotics now or in the recent past, or have had many infections, talk with your doctor.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Very bad and sometimes deadly bleeding problems have happened with Farydak (panobinostat). Talk with the doctor.
- If you are 65 or older, use Farydak (panobinostat) with care. You could have more side effects.
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for 6 months after stopping Farydak (panobinostat). Use a condom.
- If you are a man and your sex partner gets pregnant while you take Farydak (panobinostat) or within 6 months after your last dose, call your doctor right away.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- A pregnancy test will be done to show that you are NOT pregnant before starting Farydak (panobinostat). You will also need to have pregnancy tests done while taking Farydak (panobinostat). Talk with your doctor.
- Use birth control that you can trust to prevent pregnancy while taking Farydak (panobinostat) and for 3 months after care ends.
- If you get pregnant while taking Farydak (panobinostat) or within 3 months after your last dose, call your doctor right away.
How is this medicine (Farydak) best taken?
Use Farydak (panobinostat) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- This medicine is not taken every day. Be sure you know how to take it. Talk with your doctor if you have questions.
- Take with or without food.
- Swallow whole. Do not chew, open, or crush.
- Take with a full glass of water.
- If you touch a broken capsule, or the drug inside the capsule, wash the area with soap and water.
- If Farydak (panobinostat) gets in the eyes, rinse with cool water.
- Avoid star fruit, pomegranate or pomegranate juice, and grapefruit or grapefruit juice while you take Farydak (panobinostat).
- Take Farydak (panobinostat) at the same time of day.
- Keep taking Farydak (panobinostat) as you have been told by your doctor or other health care provider, even if you feel well.
- To gain the most benefit, do not miss doses.
- If you throw up after taking a dose, do not repeat the dose. Take your next dose at your normal time.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it has been 12 hours or more since the missed dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Change in color of skin to a bluish color like on the lips, nail beds, fingers, or toes.
- Chest pain or pressure.
- Fast or slow heartbeat.
- A heartbeat that does not feel normal.
- Dizziness or passing out.
- Pale skin.
- Very bad headache.
- Very upset stomach or throwing up.
- Shortness of breath.
- Swelling in the arms or legs.
- Feeling very tired or weak.
What are some other side effects of Farydak?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Not hungry.
- Upset stomach or throwing up.
- Weight loss.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Farydak?
- Store in the original container at room temperature.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Farydak (panobinostat) is refilled. If you have any questions about Farydak (panobinostat), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Farydak (panobinostat)
- Farydak Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: histone deacetylase inhibitors