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Kyprolis User Reviews & Ratings

Kyprolis has an average rating of 6.6 out of 10 from a total of 5 reviews on Drugs.com. 40% of reviewers reported a positive experience, while 20% reported a negative experience.

Condition Avg. Rating Reviews Compare
Multiple Myeloma
6.6
5 reviews for Multiple Myeloma 70 medications

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  • MtD...
  • December 17, 2017

For Multiple Myeloma "Diagnosed about a year ago at age 59. Healthy, active adult male with no other medical issues. Went to the Mayo Clinic after a local physician diagnosed MM. Mayo doc did all the testing and found high-risk genetics. Multiple sites on PET scan and about 60% plasma cells in the bone marrow biopsy. Had a hip replaced due to a pre-emergent fracture due to MM bone lesions. Guess I was pretty sick... Doc said the best treatment was K-R-D. 120 K, 80 Dex on a two-day-per-week schedule for 3 weeks each month. Revlimid 25 on a 21-day schedule. Zofran for stomach. It was a bit rough initially, but had no nausea or hair loss. Rash a couple of times, mostly just felt flu-like for a few days after chemo. One year later now... complete remission. Bone marrow biopsy normal."

6 / 10
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19 Report
  • GTa...
  • Taken for 6 months to 1 year
  • April 17, 2020

For Multiple Myeloma "After failing 5 previous therapies for MS, started taking Kyprolis + dex almost a year ago. Has become harder to take over time. Severe nausea now on treatment days, uncontrolled hypertension, headaches. Would ask oncologist to stop, but no options left other than CAR-T cell clinical trial for which I am on the list, but they are all shut down due to coronavirus. Kyprolis did dramatically slow the progression of my myeloma over the past year. I am thankful for that. Six years of constant treatment takes a significant toll on quality of life. I was diagnosed at 56."

6 / 10
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11 Report
  • My ...
  • August 10, 2017

For Multiple Myeloma "He was on it alone for 3 cycles and started on the 4th. Kappa light chains went up each month and doubled to over 11,000 before stopping it. Had been on it with Revlimid, which helped decrease light chains, but couldn't tolerate due to blood counts. Platelets needed every other day and RBCs needed weekly."

1 / 10
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6 Report

Frequently asked questions

  • Lar...
  • Taken for 1 to 6 months
  • August 30, 2024

For Multiple Myeloma "Male, age 78, with MM for 16 months, with an initial IgG of 3699. Received treatment from Moffitt Comprehensive Cancer Center in Tampa. Initial Velcade treatment but hit a plateau of +/- 1700 for my IgG. Moved to Kyprolis + Dex; saw immediate results with no severe side effects except continuing fatigue and low red blood cell count. After 4 months on Kyprolis, my IgG is 472 and my M spike is 0.30. Hopeful of short-term remission. Great experience thus far and hope to see my 80th birthday."

10 / 10
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  • Dan...
  • January 11, 2025

For Multiple Myeloma "I was diagnosed with light chain myeloma in '09. I had a transplant in late '09. For me, it was the beginning of a nightmare. I could practically write a book about it. Anyway, by 2022, I had been through more treatments than I can remember, and my myeloma was raging. Kyprolis with Darzalex brought my Kappa Lambda numbers into the lower normal range within 2 treatments. They have stayed there ever since. I quit treatment about 6 months ago because the side effects were getting more than I could deal with. I'm talking about dry heaves every 30 minutes for 2 weeks. This was against my doctor's advice, but so far, I am doing well. My numbers have never been as good as they are now. I am hoping this might help someone."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.