Generic Name: ceftazidime and avibactam (sef-TAZ-i-deem & a-vi-BAK-tam)
Brand Name: Avycaz
Avycaz is used for:
Treating bacterial infections.
Avycaz is an antibiotic. It works by killing sensitive bacteria.
Do NOT use Avycaz if:
- you are allergic to any ingredient in Avycaz or to another cephalosporin (eg, cephalexin)
- you are taking probenecid
Contact your doctor or health care provider right away if any of these apply to you.
Before using Avycaz:
Some medical conditions may interact with Avycaz. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin (eg, amoxicillin) or beta-lactam antibiotic (eg, imipenem)
- if you have kidney problems
Some MEDICINES MAY INTERACT with Avycaz. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Probenecid because it may increase the risk of Avycaz's side effects
- Hormonal birth control (eg, birth control pills) because its effectiveness may be decreased by Avycaz
This may not be a complete list of all interactions that may occur. Ask your health care provider if Avycaz may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Avycaz:
Use Avycaz as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Avycaz is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
- To clear up your infection completely, use Avycaz for the full course of treatment. Keep using it even if you feel better in a few days.
- If you miss a dose of Avycaz, call your doctor to find out what to do.
Ask your health care provider any questions you may have about how to use Avycaz.
Important safety information:
- Tell your doctor or dentist that you take Avycaz before you receive any medical or dental care, emergency care, or surgery.
- Serious and sometimes deadly allergic reactions have rarely happened with medicines like this one. Discuss any questions or concerns with your doctor.
- Avycaz only works against bacteria; it does not treat viral infections (eg, the common cold).
- Be sure to use Avycaz for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Long-term or repeated use of Avycaz may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody or watery stools occur. Do not treat diarrhea without first checking with your doctor.
- Diabetes patients-Avycaz may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
- Hormonal birth control (eg, birth control pills) may not work as well while you are using Avycaz. To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Avycaz may affect certain lab test results. Be sure your doctor and lab personnel know you are using Avycaz.
- Lab tests may be performed while you use Avycaz. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Avycaz with caution in the ELDERLY; they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using this while you are pregnant. Avycaz is found in breast milk. If you are or will be breast-feeding while you use Avycaz, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Avycaz:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Anxiety; constipation; dizziness; nausea; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal muscle movements; confusion; hallucinations; passing out; seizures; tremor.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Avycaz:
Avycaz is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.
- If you have any questions about Avycaz, please talk with your doctor, pharmacist, or other health care provider.
- Avycaz is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Avycaz or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Avycaz. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Avycaz. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Avycaz.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Avycaz (avibactam / ceftazidime)
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- Drug class: cephalosporins/beta-lactamase inhibitors