Artemether and Lumefantrine
Generic Name: Artemether and Lumefantrine (ar TEM e ther & loo me FAN treen)
Brand Name: Coartem
Uses of Artemether and Lumefantrine:
- It is used to treat malaria.
What do I need to tell my doctor BEFORE I take Artemether and Lumefantrine?
- If you have an allergy to artemether, lumefantrine, or any other part of artemether and lumefantrine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Low potassium or magnesium levels.
- If you have ever had a long QT on ECG or other heartbeat that is not normal.
- If a family member has a long QT on ECG or has ever died all of a sudden.
- If you have heart problems.
- If you have had a recent heart attack.
- If you are taking any of these drugs: Amitriptyline, carbamazepine, clomipramine, flecainide, imipramine, phenytoin, rifampin, or St. John's wort.
- If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you are taking or have taken halofantrine within a month of this medicine.
This is not a list of all drugs or health problems that interact with artemether and lumefantrine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Artemether and Lumefantrine?
- Tell all of your health care providers that you take artemether and lumefantrine. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- You may need to have an ECG checked before starting artemether and lumefantrine and while taking it. Talk with your doctor.
- Avoid grapefruit and grapefruit juice.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this medicine.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using artemether and lumefantrine while you are pregnant.
- This medicine has been shown to cause birth defects in animals. Talk with the doctor.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Artemether and Lumefantrine) best taken?
Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- To gain the most benefit, do not miss doses.
- Keep taking artemether and lumefantrine as you have been told by your doctor or other health care provider, even if you feel well.
- Take this medicine with food.
- You may crush tablet and mix with 1 or 2 teaspoons (5 or 10 mL) of water.
- Rinse cup with more water and drink.
- If you throw up within 1 hour of taking artemether and lumefantrine, take 1 more dose.
- If you throw up again after taking the second dose, call your doctor.
- If you are not able to eat food when you take this medicine, talk with your doctor.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad dizziness.
- Feeling very tired or weak.
- Trouble swallowing.
- A type of abnormal heartbeat (prolonged QT interval) can happen with artemether and lumefantrine. Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.
What are some other side effects of Artemether and Lumefantrine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Fever or chills.
- Upset stomach or throwing up.
- Belly pain.
- Not hungry.
- Feeling tired or weak.
- Muscle or joint pain.
- Not able to sleep.
- Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Artemether and Lumefantrine?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take artemether and lumefantrine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to artemether and lumefantrine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: October 4, 2017
More about artemether/lumefantrine
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Compare Alternatives
- Support Group
- En Español
- 4 Reviews – Add your own review/rating
- Drug class: antimalarial combinations
Other brands: Coartem