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How is Cotempla XR-ODT different to other brands of methylphenidate?

Answers (1)

Official Answer by Drugs.com 10 Oct 2017

Cotempla XR-ODT (methylphenidate) from Neos Therapeutics was approved in June 2017 for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients 6 to 17 years of age. It is the first once-daily, extended-release, orally disintegrating tablet (ODT) formulation of the stimulant methylphenidate. This ODT form is designed to dissolve on the tongue without the need to swallow with water. It is not approved for use in adults.

Other brands of methylphenidate on the U.S market have various dosage forms: Aptensio XR and Metadate CD are both extended release capsules; Ritalin LA is a biphasic, long-acting capsule; Concerta and Metadate ER are extended release tablets; Ritalin is an immediate release tablet given two or three times daily; Methylin is an immediate release solution given two or three times daily; Daytrana is a a skin patch worn 9 hours daily; Quillichew ER is a chewable extended-release tablet; and Quillivant XR is an extended release suspension. The brands Methylin ER and Ritalin SR have been discontinued in the U.S.

All products except Cotempla XR-ODT are indicated in age 6 years and older. All longer-acting agents are usually only given once a day, although some may may be given twice a day.

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