Does Bupropion make you gain tons of weight and also make you a very restless sleeper?

I have been on Wellbutrin for only 3 months and have gained 20 lbs. I have not changed any other medications and wasn't having a problem before. I haven't noticed a change in my sleep unless I add caffeine to my diet. The combination of Wellbutrin and caffeine causes a great deal of anxiety. I can't take the Wellbutrin after noon time or I will not be able to sleep soundly either.

I have bipolar disorder and am taking Lamictal. It wasn't helping with my depression enough, so my doc added Wellbutrin. I have lost twelve pounds in 6 weeks. It does have a stimulating effect, so I have to take it in the morning or my sleep is restless. It gives me more energy to move and less desire to eat from depression. I also take Deplin, which is amazing! I buy from brand direct pharmacy since insurance won't cover it. It is a medical grade food/folic acid that helps antidepressants work better.

I used Wellbutrin for only 4 months and gained 20 pounds! During that time I was on a strict 1200 calorie diet and daily exercise. I was crushed. I went back and read the leaflet the Pharmacy included with the medication and under side effects it states may cause marked weight loss or weight GAIN. I went back to my primary care physician and she stated that it was the one of the worst out all of that class of medication for that side effect. I was so upset. Why prescribe a medication that could cause rapid weight gain to someone who is already overweight?
I was not on any other antidepressants or mood stabilizer at the time.
Regardless if a medication is labeled "weight neutral" or not, it is how the INDIVIDUAL reacts the medication.

I on 300 mg Wellbutrin XL every morning and it did not make me gain weight and all of my medications I take seems to make me lose,weight I doesnt put on weight

I am so happy to see the responses for weight gain on Wellbutrin. I am taking 300mg ER and I do feel more energetic. However I have gained 30lbs in 5 months!!! I have done nothing different. I was excited to take it because a lot of people say they lose weight. I'm glad I am not alone. thank you so much

It's a bit too early on for me to comment on weight, but in the two weeks I've been taking Bupropion I have noticed that if I wake up late or put off taking it until I've eaten I sleep terribly that night.
It's meant to last 12 hours, so I'd try to take it 14 or 15 hours before you want to go to bed so that you have some wind down time.
If I don't have to be up too early, I also take melatonin just to ensure that I'll sleep soundly.
If I take bupropion by 9:30 am, I'm able to pop a melatonin around 11pm, and fall asleep at midnight and get a solid night's sleep.

I HAVE gained close to 60 pounds taking bupropion. I had never had an issue with my weight until taking this medicine. As for the sleeping, I don't have any trouble sleeping at night but I'm always tired.

I recently switched from celexa to Wellbutrin and have noticed I am packing on the weight... and fast! I also toss and turn all night long as well. Think I'm going back to celexa!

This drug is not known for weight gain. It's actually one of the few depressants that doesn't have that side effect. Some of the side effects are actually losing weight. When you bring up the restlessness by your trying to go to bed, it makes me think how I'm so restless when I go to bed. I can't really say but it gives me restlessness but I guess it's a possibility . I've been on this drug for over 7 years and I still feel helps me. I currently take a 150 milligrams every morning it's actually well be trained time release. It's a lot less sedating and more expensive. You can always ask your doctor if your insurance will cover the ex time release

Wellbutrin is a brand name for bupropion any antidepressant will slow down your metabolism and can result in a weight gain. Antidepressants also are anti anxiety because of this fact your digestive system is less active and you may have a tendency to do less activity during the day. However for people that take Wellbutrin or bupropion you are told to take it before 4 p.m. for the second dose for some people it gives energy and may cause anxiety or Restless sleep at night it's a hit-or-miss situation according to each individual. Also you need to speak with your doctor on the length of time that you have been taking it and should be reevaluated to see if you need a change in medication that would be more suitable for your needs. Good luck I hope you feel better.

Yes yes, I too have packed on weight. I never had weight problem until I took this. Doc says it's menopause, we'll that's been done 4 yrs ago, then thyroid, which is ok too. I been on it since 2007 now I am 208 pounds. I HATE myself. I cannot no matter how or what diet I use cannot lose it.

I know this question is old, but for all of the people saying Wellbutrin does not make you gain weight, and are steadfast in their answer, YOU'RE INFURIATINGLY IGNORANT. Sorry, but this is a touchy subject for me. Everybody is made up chemically different and therefore will react differently to substances. For me, Wellbutrin ABSOLUTELY MAKES ME GAIN WEIGHT. And for that matter exacerbates my depression. This is my third time trying it and my third time ending up much worse than where I started.

I took this med. for years. I started out taking it twice a day, morning and night, as an aide to help me stop smoking, it worked!!! Yay me!! So about a year later I cut it down to once daily, mornings. I never had trouble with my sleep from the medication! As they say though, different strokes for different folks!