Does Bupropion make you gain tons of weight and also make you a very restless sleeper?

For those that gained (believe it may be my culprit, too) can anyone tell me what happened with your weight after you weaned off? TIA

I have been on the generic for Wellbutrin since March of this year and have since gained 25 pounds. This was after I had worked so hard to drop over 35 pounds in the middle of 2018 and was able to keep it off until I started the generic for Wellbutrin. I have kept up with my exercise and still stick to a vegan diet just like i had when i lost all my weight in 2018 and was keeping it off even without being super restrictive about food and was fine, but as soon as i went on the generic i gained all the weight back in less than 6 months. I’m going cold turkey and quitting this not only for the weight gain but like others i have had horrible nightmares (when i actually do sleep) but most nights i toss and turn for hours or cannot sleep past 5am. I’m also just feeling indifferent to everything, so if this isn’t even helping me to feel good AND is making me fat well I’d rather be slightly depressed and able to fit into my clothes and get a decent nights sleep.

Yes it absolutely makes some people gain weight and I am one of them. Been on this for three to four weeks and have gained 10lbs. Exhausted, miserable from the weight gain, and don’t like it at all. Taking myself off cold turkey today. Thanks for the forum. You helped me realize this is only getting worse not better. I’m done. I’d rather deal with some authentic depression than be depressed because I’m fat, sluggish, and can’t fit in my clothes.

"Metabolic
Very common (10% or more of users): Weight loss greater than 2.3 kg (up to 28%), weight gain greater than 2.3 kg (up to 11%)
Common (1% to 10% of users): Anorexia, decreased appetite, increased appetite"
Wellbutrin is "weight neutral" meaning IF you experience a metabolic change it could go either way
"Psychiatric
Very common (10% or more of users): Insomnia (up to 45%), sedation (up to 19.8%)
Again, it can go either way. Since everyone responds differently to a medication it all depends on your individual metabolism.

You are not alone. For some reason I have been gaining weight as well and am always super hungry since upping my dosage to 300mg. It took about six months for my body to adapt to sleeping normally again when I was on 150mg. I started having weird bad dreams about 3-5 times a night. Before meds I barely remembered one dream every month or two. When I’m upped my dosage to 300mg the dreams started again but were short lived and only happened for a week or two. I still have a weird one maybe once a week, but at least it’s not 4-5 times a night.
Not sure why I’m hungrier all the time now that I’m on 300mg when it is supposed to make you lose weight. The SSRIs I tried years ago actually made me lose weight when those typically make you gain weight. I think every body’s different. Wish I had an answer about the weight thing. Go figure, the med I actually like makes me fat. :/

Yes it does make you gain weight. You lose weight at first like Prozac then start to gain weight.

I gained weight as well. I was on it a few months and gained about 20 lbs, and after I went off I lost the weight. Doctors tried to tell me it wasn't possible but it was the only thing that was changed during that time frame. It's frustrating to have my experience discounted. I understand the tendency to do this because it doesn't fit into the paradigm of what usually happens with the medication- but I wish this symptom of weight gain could be used as a clue as to what could be going on with the body's chemistry.

Again... I was taking Wellbutrin XL and only this... when I went back for my 2 week check up I had already gained 5 pounds and someone that's trying to lose weight IT IS Noticeable especially in the face... I wish the doctors would just listen to there patients sometimes

Yes! This has made me gain weight despite working out and eating healthy. I have also been suffering from fatigue, so I am wondering if the Bupropion is causing this as well. I think any drug can affect people differently. Thank you for posting this, I don’t feel alone and ‘crazy’ for not haveing the typical side affects.

I’ve read a lot of the answers on here about people not gaining weight on Wellbutrin. I did gain weight on this drug but every person is different. Every antidepressant has caused weight gain for me. I lost weight when I quit taking them.

I have been taking it for nearly a year and have put on over 20lbs... thought I was depressed before.

When I FIRST started taking generic bupropion SR (150 mg 2 x a day) in August of 2017, my appetite decreased, I became more hyper as I gained energy, and I lost about 15 lbs. I felt happier and more enthusiastic about life, and was especially happy about my weight loss. But as the year went on the extra energy kind of dimmed down and my appetite came back. I gained the weight back, plus a little more. Its as if my metabolism slowed down even more than it was before. I actually weaned myself off of it for a few months. Didn't lose or gain weight during the process. But I began taking it again in October of 2018 and didn't lose ANY weight this time. I had noticeably more energy immediately after taking it, but it wasn't as extreme as the first time this drug hit my body. I'm convinced that while in the short term it may cause weight loss, it doesn't last. At least not for everyone.