Ticarcillin Side Effects

It is possible that some side effects of ticarcillin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to ticarcillin: injectable powder for injection

Get emergency medical help if you have any of these signs of an allergic reaction while taking ticarcillin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;

  • easy bruising or bleeding, unusual weakness;

  • dry mouth, increased thirst, confusion, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting;

  • fever, chills, body aches, flu symptoms; or

  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects may be more likely to occur, such as:

  • mild diarrhea, gas, stomach pain;

  • nausea or vomiting;

  • headache;

  • skin rash or itching;

  • pain, swelling, or burning where the injection was given; or

  • vaginal yeast infection (itching or discharge).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to ticarcillin: injectable powder for injection


Gastrointestinal side effects have included nausea, vomiting, diarrhea, and pseudomembranous colitis.


Local side effects have included injection site pain and induration. Vein irritation and phlebitis may occur when undiluted ticarcillin is injected directly.


Hypersensitivity reactions have included skin rashes, pruritus, urticaria, drug fever, and anaphylaxis.


Some studies show a positive correlation between the degree of hypokalemia, the dose of ticarcillin, and the serum BUN/creatinine ratio, suggesting dehydration and higher doses are risk factors for the development of ticarcillin-associated hypokalemia.

Metabolic abnormalities have included hypernatremia and hypokalemia.


Hematologic side effects have included anemia, thrombocytopenia, leukopenia, neutropenia, and eosinophilia.


Hepatic side effects have included elevations of SGOT and SGPT.

Nervous system

Nervous system side effects may include convulsion or neuromuscular excitability with high doses.

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