Proton pump inhibitors
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Proton pump inhibitors act by irreversible inhibition of the H+/K+ ATPase, in the parietal cells of the stomach. It markedly inhibits gastric acid secretion and has a long duration of action. They are used for treatment of gastric and duodenal ulcers, gastroesophageal reflux disease and other excessive gastrointestinal acid secretory disorders.
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Medical conditions associated with proton pump inhibitors:
- Aspiration Pneumonia
- Barrett's Esophagus
- Dumping Syndrome
- Duodenal Ulcer
- Duodenal Ulcer Prophylaxis
- Erosive Esophagitis
- Gastrointestinal Hemorrhage
- GERD
- Helicobacter Pylori Infection
- Indigestion
- Multiple Endocrine Adenomas
- NSAID-Induced Gastric Ulcer
- NSAID-Induced Ulcer Prophylaxis
- Pathological Hypersecretory Conditions
- Peptic Ulcer
- Stomach Ulcer
- Stress Ulcer Prophylaxis
- Systemic Mastocytosis
- Zollinger-Ellison Syndrome
