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Medications for Diabetic Peripheral Neuropathy

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Axsain Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
capsaicin 6.0 9 reviews for capsaicin to treat Diabetic Peripheral Neuropathy
Rx/OTC B N
Generic name:
capsaicin topical
Brand names:
Zostrix Diabetic Foot Pain, Capzasin, Zostrix, Axsain, Capsin, Capzasin-HP, Capzasin-P, Menthac Arthritis Cream with Capsaicin, Qutenza, Sloan's Liniment, Zostrix Neuropathy, Capzasin Back and Body, Castiva Warming, Zostrix Sports
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Capsin Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
Capzasin Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
Capzasin-HP 1.0 1 review for Capzasin-HP to treat Diabetic Peripheral Neuropathy
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
Capzasin-P Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
Capzasin Back and Body Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
carbamazepine Off-label Rate Add review
Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Castiva Warming Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
Cymbalta 6.2 42 reviews for Cymbalta to treat Diabetic Peripheral Neuropathy
Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
duloxetine 5.7 48 reviews for duloxetine to treat Diabetic Peripheral Neuropathy
Rx C N X
Generic name:
duloxetine systemic
Brand names:
Cymbalta, Irenka
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
gabapentin Off-label 6.0 57 reviews for gabapentin to treat Diabetic Peripheral Neuropathy
Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Irenka Rate Add review
Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
Lyrica 6.2 71 reviews for Lyrica to treat Diabetic Peripheral Neuropathy
Rx C 5 X
Generic name:
pregabalin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lyrica CR Rate Add review
Rx C 5 X
Generic name:
pregabalin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Menthac Arthritis Cream with Capsaicin Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
mexiletine Off-label 8.0 1 review for mexiletine to treat Diabetic Peripheral Neuropathy
Rx C N
Generic name:
mexiletine systemic
Drug class:
group I antiarrhythmics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
nortriptyline Off-label 5.8 6 reviews for nortriptyline to treat Diabetic Peripheral Neuropathy
Rx N N X
Generic name:
nortriptyline systemic
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Nucynta ER 8.1 8 reviews for Nucynta ER to treat Diabetic Peripheral Neuropathy
Rx C 2 X
Generic name:
tapentadol systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
pregabalin 6.1 75 reviews for pregabalin to treat Diabetic Peripheral Neuropathy
Rx C 5 X
Generic name:
pregabalin systemic
Brand names:
Lyrica, Lyrica CR
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Qutenza 9.0 1 review for Qutenza to treat Diabetic Peripheral Neuropathy
Rx B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sloan's Liniment Rate Add review
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
tapentadol 8.2 9 reviews for tapentadol to treat Diabetic Peripheral Neuropathy
Rx C 2 X
Generic name:
tapentadol systemic
Brand name:
Nucynta ER
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
topiramate Off-label 7.1 21 reviews for topiramate to treat Diabetic Peripheral Neuropathy
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Zostrix 5.5 3 reviews for Zostrix to treat Diabetic Peripheral Neuropathy
Rx/OTC B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects

Frequently asked questions

View more FAQ

Alternative treatments for Diabetic Peripheral Neuropathy

The following products are considered to be alternative treatments or natural remedies for Diabetic Peripheral Neuropathy. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Diabetic Peripheral Neuropathy.

  • Evening primrose

Learn more about Diabetic Peripheral Neuropathy

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.