Tapentadol Side Effects

Brand Names: Nucynta

Please note - some side effects for Tapentadol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Tapentadol - for the Consumer

Tapentadol

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tapentadol:

Constipation; dizziness; drowsiness; dry mouth; itching; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; chest pain; cold, clammy skin; confusion; difficult or increased urination; difficult, slow, or shallow breathing; disorientation; fainting; fast, slow, or irregular heartbeat; hallucinations; headache; loss of coordination; mood or mental changes; numbness or tingling; seizures; severe dizziness, drowsiness, or lightheadedness; trouble talking, thinking, or walking; weakness or tiredness.

Side Effects by Body System

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, constipation, dry mouth, dyspepsia, abdominal discomfort, impaired gastric emptying, and decreased appetite.

Nervous system

Nervous system side effects have included dizziness, somnolence, tremor, lethargy hypoesthesia, paresthesia, disturbance in attention, sedation, dysarthria, depressed level of consciousness, memory impairment, ataxia, presyncope, syncope, abnormal coordination, and seizures.

Psychiatric

Psychiatric side effects have included insomnia, confusional state, abnormal dreams, anxiety, irritability, drug withdrawal syndrome, feeling drunk, euphoric mood, disorientation, restlessness, agitation, nervousness, and abnormal thinking.

Musculoskeletal

Musculoskeletal side effects have included arthralgia, involuntary muscle contractions, and sensation of heaviness.

Dermatologic

Dermatologic side effects have included pruritus, hyperhidrosis, generalized pruritus, and urticaria.

Cardiovascular

Cardiovascular side effects have included hot flushes, heart rate increased, heart rate decreased, edema, and decreased blood pressure.

Respiratory

Respiratory side effects have included decreased oxygen saturation, cough, dyspnea, upper respiratory tract infection, nasopharyngitis, and respiratory depression.

Genitourinary

Genitourinary side effects have included urinary tract infection, urinary hesitation, and pollakiuria.

General

General side effects have included fatigue and feeling hot.

Immunologic

Immunologic side effects have included hypersensitivity.

Ocular

Ocular side effects have included visual disturbance.

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