Tapentadol Side Effects

Brand Names: Nucynta, Nucynta ER

Please note - some side effects for Tapentadol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Tapentadol - for the Consumer

Tapentadol

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tapentadol:

Constipation; dizziness; drowsiness; dry mouth; itching; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); agitation; burning, numbness, or tingling; chest pain; cold, clammy skin; confusion; difficult or increased urination; difficult, slow, or shallow breathing; disorientation; fainting; fast, slow, or irregular heartbeat; hallucinations; loss of coordination; memory problems; mood or mental changes; seizures; severe or persistent dizziness, drowsiness, or light-headedness; trouble talking, thinking, or walking.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Tapentadol Extended-Release Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tapentadol Extended-Release Tablets:

Constipation; dizziness; drowsiness; dry mouth; headache; nausea; tiredness; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); agitation; burning, numbness, or tingling; chest pain; cold, clammy skin; confusion; difficult or increased urination; difficult, slow, or shallow breathing; disorientation; fainting; fast, slow, or irregular heartbeat; hallucinations; loss of coordination; memory problems; mood or mental changes; seizures; severe or persistent dizziness, drowsiness, or light-headedness; trouble talking, thinking, or walking.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, constipation, dry mouth, dyspepsia, abdominal discomfort, impaired gastric emptying, and decreased appetite.

Nervous system

Nervous system side effects have included dizziness, somnolence, tremor, lethargy hypoesthesia, paresthesia, disturbance in attention, sedation, dysarthria, depressed level of consciousness, memory impairment, ataxia, presyncope, syncope, abnormal coordination, and seizures. Postmarketing reports have included headache.

Psychiatric

Psychiatric side effects have included insomnia, confusional state, abnormal dreams, anxiety, irritability, drug withdrawal syndrome, feeling drunk, euphoric mood, disorientation, restlessness, agitation, nervousness, and abnormal thinking. Postmarketing reports have included hallucinations.

Musculoskeletal

Musculoskeletal side effects have included arthralgia, involuntary muscle contractions, and sensation of heaviness.

Dermatologic

Dermatologic side effects have included pruritus, hyperhidrosis, generalized pruritus, and urticaria.

Cardiovascular

Cardiovascular side effects have included hot flushes, heart rate increased, heart rate decreased, edema, and decreased blood pressure.

Respiratory

Respiratory side effects have included decreased oxygen saturation, cough, dyspnea, upper respiratory tract infection, nasopharyngitis, and respiratory depression.

Genitourinary

Genitourinary side effects have included urinary tract infection, urinary hesitation, and pollakiuria.

General

General side effects have included fatigue and feeling hot.

Immunologic

Immunologic side effects have included hypersensitivity.

Ocular

Ocular side effects have included visual disturbance.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.