Capzasin-P Side Effects
Generic Name: capsaicin topical
Note: This page contains information about the side effects of capsaicin topical. Some of the dosage forms included on this document may not apply to the brand name Capzasin-P.
Not all side effects for Capzasin-P may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to capsaicin topical: topical cream, topical film, topical gel/jelly, topical liquid, topical lotion, topical ointment, topical pad, topical patch extended release, topical stick
In addition to its needed effects, some unwanted effects may be caused by capsaicin topical (the active ingredient contained in Capzasin-P). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking capsaicin topical:More common - all forms
- Burning, itching, dryness, pain, redness, swelling, or soreness at the application site
- cough-producing mucus
- difficulty with breathing
- shortness of breath or troubled breathing
- sore throat
- stuffy or runny nose
- tightness in the chest or wheezing
- Blurred vision
- pounding in the ears
- slow or fast heartbeat
- Bloating or swelling of the face, arms, hands, lower legs, or feet
- increased sensitivity to pain
- increased sensitivity to touch
- rapid weight gain
- tingling in the hands and feet
- unsteadiness or awkwardness
- unusual weight gain or loss
- weakness in the arms, hands, legs, or feet
Some of the side effects that can occur with capsaicin topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common - patch only
- muscle aches
- pain or tenderness around the eyes and cheekbones
- unusual tiredness or weakness
- Abnormal skin color
- change in taste
- loss of taste
For Healthcare Professionals
Applies to capsaicin topical: compounding powder, topical cream, topical film, topical gel, topical kit, topical liquid, topical lotion, topical stick
Local side effects have included transient stinging, burning, pain, edema, swelling, papules, dermatitis, bruising, urticaria, inflammation, exfoliation, erythema, hyperalgesia, paresthesia, hyperesthesia, anesthesia, pruritus, dryness, and abnormal skin color at the application site.[Ref]
In general, no serious adverse events have been reported.[Ref]
Nervous system side effects have included headache, burning sensation, peripheral sensory neuropathy, dizziness, dysgeusia, hyperesthesia, and hypoesthesia.[Ref]
Gastrointestinal side effects have included nausea and vomiting.[Ref]
Cardiovascular side effects have included transient hypertension.[Ref]
Respiratory side effects have included cough and throat irritation, nasopharyngitis, bronchitis, and sinusitis.[Ref]
1. "Product Information. Axsain (capsaicin topical)." Rodlen Laboratories, Vernon Hills, IL.
2. "Product Information. Qutenza (capsaicin topical)." NeurogesX Inc, San Mateo, CA.
3. Babbar S, Marier JF, Mouksassi MS, et al. "Pharmacokinetic analysis of capsaicin after topical administration of a high-concentration capsaicin patch to patients with peripheral neuropathic pain." Ther Drug Monit 31 (2009): 502-10
More about Capzasin-P (capsaicin topical)
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.