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Medications for Head Lice

Other names: Lice, head; Nits; Pediculosis capitis, head lice

Head lice are small, parasitic insects that infest hair on the head of people, and feed on blood from the scalp. Their six legs allow them to grasp and wander between hairs.

Drugs used to treat Head Lice

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
malathion 8.6 11 reviews for malathion to treat Head Lice
Rx B N
Generic name:
malathion topical
Drug class:
topical anti-infectives
For consumers:
side effects
For professionals:
AHFS DI Monograph, Prescribing Information
spinosad 7.1 12 reviews for spinosad to treat Head Lice
Rx B N
Generic name:
spinosad topical
Brand name:
Natroba
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
permethrin 2.0 7 reviews for permethrin to treat Head Lice
Rx/OTC B N
Generic name:
permethrin topical
Brand names:
Elimite, Nix Complete Lice Treatment System, Acticin, Nix, Lice Bedding Spray, Nix Cream Rinse, Nix Lice Control, RID Home Lice Control Spray for Surfaces
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Elimite Rate Add review
Rx/OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Nix Complete Lice Treatment System 1.0 3 reviews for Nix Complete Lice Treatment System to treat Head Lice
OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
Sklice 6.6 46 reviews for Sklice to treat Head Lice
OTC C N
Generic name:
ivermectin topical
Drug class:
topical anti-infectives, topical anti-rosacea agents
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Natroba 8.0 5 reviews for Natroba to treat Head Lice
Rx B N
Generic name:
spinosad topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
piperonyl butoxide / pyrethrins 3.0 2 reviews for piperonyl butoxide / pyrethrins to treat Head Lice
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Brand names:
A-200 Lice Treatment, Lice Treatment, RID, Good Sense Lice Killing Shampoo, Step 1, Licide, Rid Pediculicide, Pronto Lice Kill System, Tegrin-LT Lice Treatment Kit, Tisit, Triple X Pediculicide
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph
A-200 Lice Treatment Rate Add review
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
Lice Treatment Rate Add review
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
ivermectin 6.5 47 reviews for ivermectin to treat Head Lice
Rx/OTC C N
Generic name:
ivermectin topical
Brand name:
Sklice
Drug class:
topical anti-infectives, topical anti-rosacea agents
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
sodium chloride Rate Add review
OTC C N
Generic name:
sodium chloride topical
Drug class:
miscellaneous topical agents
For consumers:
For professionals:
Prescribing Information
Acticin Rate Add review
Rx/OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
benzyl alcohol 8.0 1 review for benzyl alcohol to treat Head Lice
Rx/OTC B N
Generic name:
benzyl alcohol topical
Drug class:
topical anti-infectives
For consumers:
side effects
Nix Rate Add review
OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
lindane 3.0 1 review for lindane to treat Head Lice
Rx C N
Generic name:
lindane topical
Drug class:
topical anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Lice Bedding Spray Rate Add review
Rx/OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
Nix Cream Rinse Rate Add review
OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
Nix Lice Control Rate Add review
OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
RID 3.0 2 reviews for RID to treat Head Lice
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
acetic acid Rate Add review
Rx/OTC N N
Generic name:
acetic acid topical
Drug class:
topical anti-infectives
For consumers:
side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Good Sense Lice Killing Shampoo, Step 1 Rate Add review
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
Licide Rate Add review
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
RID Home Lice Control Spray for Surfaces Rate Add review
Rx/OTC B N
Generic name:
permethrin topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects
Rid Pediculicide Rate Add review
Rx/OTC N N
Generic name:
piperonyl butoxide / pyrethrins topical
Drug class:
topical anti-infectives
For consumers:
dosage, side effects

Frequently asked questions

View more FAQ

Learn more about Head Lice

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.