Spinosad Topical Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 15, 2025.
Applies to spinosad topical: topical application suspension.
Precautions
This medicine contains benzyl alcohol which may cause serious reactions to newborn, premature, or low-birthweight infants. Check with your doctor if you are concerned.
Head lice and scabies can be easily spread from one person to another by direct contact with clothing, hats, scarves, bedding, towels, washcloths, hairbrushes and combs, or hairs from infected persons. All members of your household should be checked for head lice or scabies, and should receive treatment if they are found to be infected. If you have any questions about this, check with your doctor.
To prevent spread of lice or scabies: Dry-clean or wash your clothes, bedding, and personal items (eg, washcloths, towels, hats, scarves, combs, brushes, hairpieces, and wigs) in hot, soapy water and dry them in a hot dryer.
Do not use this medicine for a skin, hair, or scalp problem that has not been checked by your doctor.
Common side effects of spinosad topical
Some side effects of spinosad topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common side effects
Rare side effects
- dryness of the scalp or skin
- hair loss
- thinning of the hair
Serious side effects of spinosad topical
Along with its needed effects, spinosad topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
See also:
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For healthcare professionals
Applies to spinosad topical: topical suspension.
Local adverse events
- Common (1% to 10%): Application site erythema, application site irritation
- Uncommon (0.1% to 1%): Application site dryness, application site exfoliation[Ref]
Ocular
- Common (1% to 10%): Ocular erythema[Ref]
Dermatologic
References
1. (2011) "Product Information. Natroba (spinosad topical)." ParaPRO LLC
2. Popescu CM, Popescu R (2012) "Efficacy and safety of spinosad cream rinse for head lice." Arch Dermatol, 148, p. 1065-9
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Further information
Spinosad topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.