Spinosad use while Breastfeeding

Summary of Use during Lactation

No information is available on the clinical use of spinosad during breastfeeding. Because it is not systemically absorbed after topical application, it should not be present in breastmilk. However, the topical suspension contains benzyl alcohol, which may be systemically absorbed through the skin. High doses of benzyl alcohol are potentially toxic to neonates, but it is unlikely that doses this high reach breastmilk. The manufacturer states that mothers concerned about benzyl alcohol could pump and discard breastmilk for 8 hours, but this is probably unnecessary. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Permethrin, Pyrethrins

References

1.

Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. [PubMed: 14623482]

Substance Name

Spinosad

CAS Registry Number

168316-95-8

Drug Class

• Breast Feeding
• Lactation
• Insecticides