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Natroba Side Effects

Generic name: spinosad topical

Medically reviewed by Last updated on Dec 23, 2023.

Note: This document contains side effect information about spinosad topical. Some dosage forms listed on this page may not apply to the brand name Natroba.

Applies to spinosad topical: topical application suspension.

Serious side effects of Natroba

Along with its needed effects, spinosad topical (the active ingredient contained in Natroba) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Other side effects of Natroba

Some side effects of spinosad topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common


For Healthcare Professionals

Applies to spinosad topical: topical suspension.


Common (1% to 10%): Application site erythema, application site irritation

Uncommon (0.1% to 1%): Application site dryness, application site exfoliation[Ref]


Common (1% to 10%): Ocular erythema[Ref]


Uncommon (0.1% to 1%): Alopecia, dry skin[Ref]


1. Product Information. Natroba (spinosad topical). ParaPRO LLC. 2011.

2. Popescu CM, Popescu R. Efficacy and safety of spinosad cream rinse for head lice. Arch Dermatol. 2012;148:1065-9.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.