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Sklice Side Effects

Generic Name: ivermectin topical

Note: This document contains side effect information about ivermectin topical. Some of the dosage forms listed on this page may not apply to the brand name Sklice.

For the Consumer

Applies to ivermectin topical: topical application cream, topical application lotion

Along with its needed effects, ivermectin topical (the active ingredient contained in Sklice) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of ivermectin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Burning, itching, redness, or stinging of the skin
  • burning, dry, or itching eyes
  • dandruff
  • discharge or excessive tearing
  • dry skin
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

For Healthcare Professionals

Applies to ivermectin topical: topical cream, topical lotion


The most frequently reported side effects included skin burning sensation, skin irritation, pruritus, and dry skin, occurring in 1% or less of patients.[Ref]


Common (1% to 10%): Burning sensation
Uncommon (0.1% to 1%): Skin irritation, pruritus, dry skin
Frequency not reported: Erythema, contact dermatitis, dandruff[Ref]


Common (1% to 10%): Muscle strain, back pain[Ref]

Nervous system

Common (1% to 10%): Headache


Common (1% to 10%): Nasopharyngitis, upper respiratory tract infection, sinusitis[Ref]


Common (1% to 10%): Seasonal allergy[Ref]


Frequency not reported: Conjunctivitis, ocular hyperemia, eye irritation[Ref]


Common (1% to 10%): Urinary tract infection[Ref]


1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Soolantra (ivermectin topical)." Galderma Laboratories Inc, Cranbury, NJ.

4. "Product Information. Sklice (ivermectin topical)." Arbor Pharmaceuticals, Atlanta, GA.

Some side effects of Sklice may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.