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Lindane topical Side Effects

Medically reviewed by Last updated on Jul 25, 2023.

Applies to lindane topical: topical shampoo.


Topical route (Shampoo)

Lindane shampoo should only be used in patients who cannot tolerate or have failed first-line treatment with safer medications for the treatment of lice. Seizures and deaths have been reported following lindane shampoo use with repeat or prolonged application, but also in rare cases following a single application according to directions. Lindane shampoo should be used with caution in infants, children, the elderly, and individuals with other skin conditions, and those who weigh less than 110 pounds (50 kg) as they may be at risk of serious neurotoxicity. Lindane shampoo is contraindicated in premature infants and individuals with known uncontrolled seizure disorders. Instruct patients on the proper use of lindane shampoo, the amount to apply, how long to leave it on, and avoiding retreatment. Inform patients that itching occurs after the successful killing of lice and is not necessarily an indication for retreatment with lindane shampoo.

Serious side effects of Lindane topical

Along with its needed effects, lindane topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking lindane topical:


After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, Check with your doctor immediately if you notice the following side effects:

Serious side effects have resulted in patients using lindane. Sometime it has occurred even when used according to the labeled directions. Serious side effects have been reported following lindane use with repeat or prolonged use, but also in rare cases following a single application. You should discuss these possible effects with your doctor.

For Healthcare Professionals

Applies to lindane topical: topical liquid, topical lotion, topical shampoo.

Nervous system

Frequency not reported: Dizziness, seizures, other central nervous system stimulation

Postmarketing reports: Headache, paresthesia[Ref]


Frequency not reported: Death

Postmarketing reports: Pain[Ref]


Frequency not reported: Irritant dermatitis

Postmarketing reports: Alopecia, dermatitis, pruritus, urticaria[Ref]


1. Product Information. Lindane (lindane topical). VersaPharm Inc. 2016.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.