Zovirax Cream Side Effects

Generic name: acyclovir topical

Medically reviewed by Drugs.com. Last updated on Oct 24, 2023.

Note: This document provides detailed information about Zovirax Cream Side Effects associated with acyclovir topical. Some dosage forms listed on this page may not apply specifically to the brand name Zovirax Cream.

Applies to acyclovir topical: topical cream, topical ointment.

Common side effects of Zovirax Cream

Some side effects of acyclovir topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• mild pain, burning, or stinging

Less common

• itching

Rare

• itching, stinging, or redness of the genital area
• skin rash

Serious side effects of Zovirax Cream

Along with its needed effects, acyclovir topical (the active ingredient contained in Zovirax Cream) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

For healthcare professionals

Applies to acyclovir topical: topical cream, topical ointment.

General

The more commonly reported adverse effects have included local application site reactions including transient stinging and burning.^[Ref]

Dermatologic

• Very common (10% or more): Mild pain including transient burning and stinging (30%) at application site
• Common (1% to 10%): Local pruritus
• Rare (less than 0.1%): Erythema
• Frequency not reported: Dry lips, desquamation, dryness of skin, cracked lips, burning skin, flakiness of skin
• Postmarketing reports: Contact dermatitis, eczema^[Ref]

The incidence of events between the drug and placebo group appears to be similar. Where sensitivity tests have been conducted, the reactive substance has often been the component of the cream rather than the active drug.^[Ref]

Hypersensitivity

• Postmarketing reports: Angioedema, anaphylaxis

Cardiovascular

• Postmarketing reports: Edema

Further information

Zovirax Cream side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer