Vumerity Side Effects
Generic name: diroximel fumarate
Medically reviewed by Drugs.com. Last updated on July 14, 2020.
Note: This document contains side effect information about diroximel fumarate. Some of the dosage forms listed on this page may not apply to the brand name Vumerity.
For the Consumer
Applies to diroximel fumarate: oral capsule delayed release
Side effects requiring immediate medical attention
Along with its needed effects, diroximel fumarate (the active ingredient contained in Vumerity) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking diroximel fumarate:
- Cough or hoarseness
- fever or chills
- lower back or side pain
- painful or difficult urination
Incidence not known
- Back pain
- bloating of the stomach
- blurred vision
- dark urine
- difficulty with swallowing
- fast heartbeat
- hives, itching, or skin rash
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- light-colored stools
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- stomach pain
- tightness in the chest
- unusual tiredness or weakness
- yellow eyes or skin
Side effects not requiring immediate medical attention
Some side effects of diroximel fumarate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- feeling of warmth
- redness of the face, neck, arms and occasionally, upper chest
For Healthcare Professionals
Applies to diroximel fumarate: oral delayed release capsule
Common (1% to 10%): Lymphopenia[Ref]
Frequency not reported: Progressive multifocal leukoencephalopathy (PML), serious infections[Ref]
Common (1% to 10%): Albumin urine present[Ref]
Common (1% to 10%): Aspartate aminotransferase increased
Frequency not reported: Liver injury
Postmarketing reports: Liver function abnormalities (elevations in transaminases 3 times ULN or greater with concomitant elevations in total bilirubin greater than 2 times ULN)[Ref]
Very common (10% or more): Flushing (40%)[Ref]
Very common (10% or more): Abdominal pain (18%), diarrhea (14%), nausea (12%)
Common (1% to 10%): Vomiting[Ref]
1. "Product Information. Vumerity (diroximel fumarate)." Alkermes, Inc, Cambridge, MA.
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More about Vumerity (diroximel fumarate)
- During Pregnancy
- Dosage Information
- Imprints, Shape & Color Data
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: selective immunosuppressants
- FDA Approval History
Related treatment guides
Some side effects may not be reported. You may report them to the FDA.