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Vi-Atro Side Effects

Generic Name: atropine / diphenoxylate

Note: This document contains side effect information about atropine / diphenoxylate. Some of the dosage forms listed on this page may not apply to the brand name Vi-Atro.

For the Consumer

Applies to atropine / diphenoxylate: oral solution, oral tablet

Along with its needed effects, atropine / diphenoxylate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking atropine / diphenoxylate:

  • Bloating
  • constipation
  • loss of appetite
  • stomach pain (severe) with nausea and vomiting

Check with your doctor immediately if any of the following side effects occur while taking atropine / diphenoxylate:

  • Blurred vision (continuing) or changes in near vision
  • drowsiness (severe)
  • dryness of mouth, nose, and throat (severe)
  • fast heartbeat
  • shortness of breath or troubled breathing (severe)
  • unusual excitement, nervousness, restlessness, or irritability
  • unusual warmth, dryness, and flushing of the skin

Some side effects of atropine / diphenoxylate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare
  • Blurred vision
  • confusion
  • difficult urination
  • dizziness or light-headedness
  • drowsiness
  • dryness of skin and mouth
  • fever
  • headache
  • increased body temperature
  • mental depression
  • numbness of hands or feet
  • skin rash or itching
  • swelling of the gums

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Rare
  • Increased sweating
  • muscle cramps
  • nausea or vomiting
  • shivering or trembling
  • stomach cramps

For Healthcare Professionals

Applies to atropine / diphenoxylate: oral liquid, oral tablet

Nervous system

Frequency not reported: Numbness of extremities, sedation/drowsiness, dizziness, headache, somnolence[Ref]

Gastrointestinal

Frequency not reported: Swelling of the gums, toxic megacolon, paralytic ileus, pancreatitis, vomiting, nausea, abdominal discomfort, constipation[Ref]

Cardiovascular

Frequency not reported: Tachycardia, cardiac irregularities (e.g. arrhythmias, bradycardia, palpitations)[Ref]

Ocular

Frequency not reported: Increased intraocular pressure, dilation of pupils with loss of accommodation, photophobia, angle closure glaucoma[Ref]

Genitourinary

Frequency not reported: Urinary retention, difficulty in micturition[Ref]

Psychiatric

Frequency not reported: Euphoria, depression, confusion, restlessness, hallucinations[Ref]

Dermatologic

Frequency not reported: Urticaria, pruritus, flushing[Ref]

Hypersensitivity

Frequency not reported: Anaphylaxis, angioneurotic edema[Ref]

Metabolic

Frequency not reported: Anorexia[Ref]

Respiratory

Frequency not reported: Respiratory depression in children[Ref]

Other

Frequency not reported: Malaise/lethargy, hyperthermia, dryness of the skin and mucous membranes[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Lomotil (diphenoxylate-atropine)." Searle, Skokie, IL.

Some side effects of Vi-Atro may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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