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Triostat Side Effects

Generic name: liothyronine

Medically reviewed by Drugs.com. Last updated on May 13, 2025.

Note: This document provides detailed information about Triostat Side Effects associated with liothyronine. Some dosage forms listed on this page may not apply specifically to the brand name Triostat.

Applies to liothyronine: intravenous solution.

Other dosage forms:

Important warnings This medicine can cause some serious health issues

Intravenous route (solution)

In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction.

Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood and urine tests will be needed to check for unwanted effects .

Liothyronine should not be given to patients who are also using artificial rewarmers .

Liothyronine should not be used for the treatment of obesity or for the purpose of losing weight. This medicine is ineffective for weight reduction and when taken in larger amount, it may cause more serious medical conditions .

Hypothyroidism can sometimes cause infertility in men and women. Liothyronine should not be used for the treatment of infertility unless it is caused by hypothyroidism .

Serious side effects of Triostat

Along with its needed effects, liothyronine (the active ingredient contained in Triostat) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking liothyronine:

More common side effects

  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat

Less common side effects

  • bluish color
  • blurred vision
  • changes in skin color
  • chest pain or discomfort
  • chest tightness or heaviness
  • confusion
  • decreased urine output
  • dilated neck veins
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • extreme fatigue
  • fever
  • headache
  • heart stops
  • irregular breathing
  • nausea
  • nervousness
  • no breathing
  • no pulse or blood pressure
  • pain or discomfort in arms, jaw, back or neck
  • pain, tenderness, swelling of foot or leg
  • pounding in the ears
  • shortness of breath
  • sweating
  • swelling of face, fingers, feet, or lower legs
  • troubled breathing
  • unconscious
  • unusual tiredness or weakness
  • vomiting
  • weight gain
  • wheezing

Symptoms of overdose

Other side effects of Triostat

Some side effects of liothyronine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

  • twitching

For healthcare professionals

Applies to liothyronine: compounding powder, intravenous solution, oral tablet.

General adverse events

Reported side effects are usually indicative of excessive dosage and will usually disappear when the dose is reduced or treatment is stopped.[Ref]

Cardiovascular

Nervous system

Dermatologic

Musculoskeletal

Gastrointestinal

Immunologic

Local

Psychiatric

Genitourinary

Other

References

1. (2001) "Product Information. Cytomel (liothyronine)." Monarch Pharmaceuticals Inc

2. (2005) "Product Information. Triostat (liothyronine)." JHP Pharmaceuticals

3. Cerner Multum, Inc. "UK Summary of Product Characteristics."

4. Cerner Multum, Inc. "Australian Product Information."

Does Triostat interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Further information

Triostat side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.