Sotylize Side Effects

Generic name: sotalol

Medically reviewed by Drugs.com. Last updated on Jun 10, 2024.

Note: This document provides detailed information about Sotylize Side Effects associated with sotalol. Some dosage forms listed on this page may not apply specifically to the brand name Sotylize.

Applies to sotalol: intravenous solution.

Other dosage forms:

• oral solution, oral tablet

Important warnings This medicine can cause some serious health issues

Intravenous route (solution)

Sotalol can cause life threatening ventricular tachycardia associated with QT interval prolongation.

To minimize the risk of drug induced arrythmia, initiate or uptitrate intravenous sotalol in a facility that can provide continuous electrocardiographic monitoring and cardiac resuscitation.

Do not initiate intravenous sotalol therapy if the baseline QTc is longer than 450 ms.

If the QTc prolongs to 500 ms or greater, reduce the dose or discontinue.

Serious side effects of Sotylize

Along with its needed effects, sotalol (the active ingredient contained in Sotylize) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking sotalol:

More common

• blurred vision
• chest pain, discomfort, or tightness
• confusion
• difficult or labored breathing
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fast, irregular, pounding, or racing heartbeat or pulse
• increased sweating
• slow or irregular heartbeat
• sweating
• swelling
• trouble breathing
• unusual tiredness or weakness

Less common

• arm, back, or jaw pain
• body aches or pain
• chest heaviness
• chills
• cold hands and feet
• cough
• decreased urine output
• diarrhea
• difficulty with breathing
• difficulty with speaking
• dilated neck veins
• dizziness
• double vision
• ear congestion
• fainting
• fever
• general feeling of discomfort or illness
• headache
• inability to move the arms, legs, or facial muscles
• inability to speak
• irregular breathing
• joint pain
• loss of appetite
• loss of voice
• muscle aches and pains
• nausea
• nervousness
• noisy breathing
• pounding in the ears
• runny or stuffy nose
• shivering
• slow speech
• sneezing
• sore throat
• swelling of the face, fingers, feet, or lower legs
• trouble sleeping
• vomiting
• weight gain

Incidence not known

• black, tarry stools
• bleeding gums
• blood in the urine or stools
• blue lips and fingernails
• coughing that sometimes produces a pink frothy sputum
• difficult, fast, or noisy breathing
• increased sweating
• painful or difficult urination
• pale skin
• pinpoint red spots on the skin
• sores, ulcers, or white spots on the lips or in the mouth
• swelling in the legs and ankles
• swollen glands
• unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur while taking sotalol:

Symptoms of overdose

• anxiety
• blurred vision
• chest pain or discomfort
• cold sweats
• confusion
• cool, pale skin
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• depression
• fast, pounding, or irregular heartbeat or pulse
• increased hunger
• nightmares
• seizures
• shakiness
• slow or irregular heartbeat
• slurred speech
• sweating
• unusual tiredness or weakness

Other side effects of Sotylize

Some side effects of sotalol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• abnormal ejaculation
• back pain
• bloated feeling
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• decreased appetite
• decreased interest in sexual intercourse
• excess air or gas in the stomach or intestines
• full feeling
• inability to have or keep an erection
• loss in sexual ability, desire, drive, or performance
• muscle or bone pain
• passing gas
• rash
• stomach distension

Incidence not known

• hair loss or thinning of the hair
• itching skin
• loss or thinning of the hair
• muscle aches, cramps, pains, or stiffness
• pain, itching, burning, swelling, or a lump under your skin where the needle is placed
• severe sunburn
• swollen joints

For healthcare professionals

Applies to sotalol: intravenous solution, oral solution, oral tablet.

Cardiovascular

• Very common (10% or more): Bradycardia (up to 16%), chest pain (up to 16%), palpitation (up to 14%)
• Common (1% to 10%): Edema, abnormal ECG, hypotension, proarrhythmia (including Torsade de Pointes), syncope, heart failure, presyncope, vasodilation, Automatic Implantable Cardioverter-Defibrillator (AICD) discharge, hypertension, stroke^[Ref]

Nervous system

• Very common (10% or more): Fatigue (up to 20%), dizziness (up to 20%), asthenia (up to 13%), light headedness (up to 12%)
• Common (1% to 10%): Headache, perspiration, paresthesia^[Ref]

Respiratory

• Very common (10% or more): Dyspnea (up to 21%)
• Common (1% to 10%): Pulmonary problem, upper respiratory tract problem, asthma^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea/vomiting (up to 10%)
• Common (1% to 10%): Appetite disorder, diarrhea, dyspepsia, abdominal pain, colon problem, flatulence, cramps^[Ref]

Metabolic

• Common (1% to 10%): Weight change^[Ref]

Dermatologic

• Common (1% to 10%): Rash^[Ref]

Musculoskeletal

• Common (1% to 10%): Extremity pain, back pain^[Ref]

Genitourinary

• Common (1% to 10%): Genitourinary disorder, sexual dysfunction^[Ref]

Hematologic

• Common (1% to 10%): Bleeding^[Ref]

Immunologic

• Common (1% to 10%): Infection^[Ref]

Local

• Common (1% to 10%): Localized pain^[Ref]

Ocular

• Common (1% to 10%): Vision problem^[Ref]

Other

• Common (1% to 10%): Fever, abnormal lab value
• Frequency not reported: Taste abnormalities, hearing disturbances^[Ref]

Psychiatric

• Common (1% to 10%): Depression, sleep problem, altered consciousness, anxiety, mood change^[Ref]

Frequently asked questions

• What's the difference between Sotalol and Sotalol AF?

Further information

Sotylize side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer