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What is the difference between Sotalol and Sotalol AF?

Medically reviewed by Drugs.com. Last updated on Nov 2, 2020.

Is there an additional drug or different salt used?

Official Answer

by Drugs.com

Sotalol AF is specifically used for maintenance of normal sinus rhythm [delay in time to recurrence of atrial fibrillation/atrial flutter (AFIB/AFL)] in patients with symptomatic AFIB/AFL who are currently in sinus rhythm.
Plain Sotalol is not approved for AFIB/AFL indication and should not be substituted for Sotalol AF because only Sotalol AF is distributed with a patient package insert that is appropriate for patients with AFIB/AFL.

[Extracted from https://www.drugs.com/pro/betapace.html
Sotalol hydrochloride (Betapace®) is used to minimize the risk of induced arrhythmia, patients initiated or reinitiated on Betapace® should be placed for a minimum of three days (on their maintenance dose) in a facility that can provide cardiac resuscitation and continuous electrocardiographic monitoring. Creatinine clearance should be calculated prior to dosing.

Sotalol is also indicated for the maintenance of normal sinus rhythm [delay in time to recurrence of atrial fibrillation/atrial flutter (AFIB/AFL)] in patients with symptomatic AFIB/AFL who are currently in sinus rhythm and is marketed under the brand name Betapace AF™. Betapace is not approved for the AFIB/AFL indication and should not be substituted for Betapace AF because only Betapace AF is distributed with a patient package insert that is appropriate for patients with AFIB/AFL.]

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