Slynd Side Effects

Generic name: drospirenone

Medically reviewed by Drugs.com. Last updated on Apr 4, 2025.

Note: This document provides detailed information about Slynd.

Applies to drospirenone: oral tablet Side Effects associated with drospirenone. Some dosage forms listed on this page may not apply specifically to the brand name Slynd.

Applies to drospirenone: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may also be needed to check for unwanted effects.

Although you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.

If you suspect that you may be pregnant, check with your doctor right away.

You might have some light bleeding or spotting, especially during the first 3 months of using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than a few days in a row, call your doctor.

Check with your doctor right away if you miss a menstrual period. Missed periods may occur if you skip one or more tablets and have not taken your pills exactly as directed. If you miss two periods in a row, talk to your doctor. You might need a pregnancy test.

Do not use this medicine if you smoke cigarettes or if you are over 35 years of age. If you smoke while using birth control pills containing drospirenone (the active ingredient contained in Slynd) you increase your risk of having a blood clot, heart attack, or stroke. Your risk is even higher if you are over age 35, if you have diabetes, high blood pressure, high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. Keep your diabetes under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.

Using this medicine may increase your risk of having blood clotting problems. Check with your doctor right away if you have pain in the chest, groin, or legs, especially the calves, difficulty with breathing, a sudden, severe headache, slurred speech, a sudden, a sudden loss of coordination, or vision changes while using this medicine.

This medicine may cause bone problems (eg, loss of bone mineral density). Check with your doctor right away if you have pain in the back, ribs, arms, or legs or a decrease in height.

Using this medicine may increase your risk of having cervical cancer. Talk with your doctor about this risk. Check with your doctor right away if you experience abnormal vaginal bleeding.

Check with your doctor right away if you have pain or tenderness in the stomach, dark urine, pale stools, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

You may have a higher risk of an ectopic pregnancy (occurs outside the womb) if you get pregnant while using this medicine. This can be a serious and life-threatening condition. It can also cause problems that may make it harder for you to become pregnant in the future.

This medicine may affect your blood sugar levels. Check with your doctor right away if you have increased thirst or increased urination. If you notice a change in the results of your urine or blood sugar tests, or if you have any questions, check with your doctor.

This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to become more depressed. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. If you or your caregiver notice any of these side effects, tell your doctor right away.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.

Serious side effects of Slynd

Along with its needed effects, drospirenone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking drospirenone:

Other side effects of Slynd

Some side effects of drospirenone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to drospirenone: oral tablet, oral tablet chewable.

General adverse events

The most commonly reported adverse reactions have included acne, abnormal uterine bleeding, headache, breast pain, increased weight, dysmenorrhea, nausea, vaginal hemorrhage, decreased libido, breast tenderness, and irregular menstruation.^[Ref]

Genitourinary

• Very common (10% or more): Unscheduled bleeding in cycle 1 (64.4%); unscheduled bleeding in cycle 13 (40.3%)
• Common (1% to 10%): Metrorrhagia, dysmenorrhea, vaginal hemorrhage, irregular menstruation
• Frequency not reported: Amenorrhea

Metabolic

• Common (1% to 10%): Increased weight
• Frequency not reported: Hyperkalemia

Endocrine

• Common (1% to 10%): Breast pain, breast tenderness

Psychiatric

• Common (1% to 10%): Decreased libido

Nervous system

• Common (1% to 10%): Headache

Dermatologic

• Common (1% to 10%): Acne

Gastrointestinal

• Common (1% to 10%): Nausea

See also:

Further information

Slynd side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer