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Santyl Side Effects

Generic name: collagenase topical

Medically reviewed by Drugs.com. Last updated on Aug 14, 2024.

Note: This document provides detailed information about Santyl.

Applies to collagenase topical: topical application ointment Side Effects associated with collagenase topical. Some dosage forms listed on this page may not apply specifically to the brand name Santyl.

Applies to collagenase topical: topical application ointment.

Precautions

It is important that your doctor check your progress at regular visits to see if the medicine is working properly.

If your skin problem does not improve or if it becomes worse, check with your doctor.

Serious side effects of Santyl

Along with its needed effects, collagenase topical (the active ingredient contained in Santyl) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking collagenase topical:

Incidence not known

  • chest tightness
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • fever
  • hives, itching, skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • redness of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • trouble breathing

Other side effects of Santyl

Some side effects of collagenase topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • redness around the wound area

For healthcare professionals

Applies to collagenase topical: compounding powder, topical ointment.

General adverse events

The most commonly reported side effect was erythema.[Ref]

Hypersensitivity

Dermatologic

See also:

References

1. (2002) "Product Information. Santyl (collagenase topical)." Knoll Pharmaceutical Company

Further information

Santyl side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.