Prodrox Side Effects
Generic Name: hydroxyprogesterone
Note: This page contains side effects data for the generic drug hydroxyprogesterone. It is possible that some of the dosage forms included below may not apply to the brand name Prodrox.
For the Consumer
Applies to hydroxyprogesterone: intramuscular oil, intramuscular solution
As well as its needed effects, hydroxyprogesterone (the active ingredient contained in Prodrox) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking hydroxyprogesterone, check with your doctor or nurse immediately:More common:
- Pain, itching, or swelling at the injection site
- Small lumps at the injection site
- chest pain
- dizziness or lightheadedness
- fast heartbeat
- redness, tenderness, or warmth on the skin
- sudden shortness of breath or troubled breathing
Minor Side Effects
Some hydroxyprogesterone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common:
- Hives or welts
- skin rash
For Healthcare Professionals
Applies to hydroxyprogesterone: compounding powder, intramuscular solution
Genitourinary side effects have included admission for preterm labor, preeclampsia or gestational hypertension, gestational diabetes, and oligohydramnios. Postmarketing side effects include urinary tract infection, cervical incompetence, premature rupture of membranes, cervical dilation, and shortened cervix.[Ref]
Local side effects have included injection site pain, swelling, pruritus, and nodules. Postmarketing side effects include local injection site reactions of erythema, urticaria, rash, irritation, hypersensitivity, and warmth.[Ref]
Gastrointestinal side effects have included nausea and diarrhea. Postmarketing side effects include vomiting.[Ref]
Dermatologic side effects have included pruritus and urticaria. Postmarketing side effects include rash.[Ref]
Nervous system side effects include postmarketing reports of headache and dizziness.
Respiratory side effects include postmarketing reports of dyspnea and chest discomfort.
Other side effects include postmarketing reports of fatigue, fever, and hot flashes/flushes.
1. "Product Information. Makena (hydroxyprogesterone)." Ther-Rx Corporation, Bridgeton, MO.
It is possible that some side effects of Prodrox may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about Prodrox (hydroxyprogesterone)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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