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Plenvu Side Effects

Generic name: polyethylene glycol 3350 with electrolytes

Medically reviewed by Drugs.com. Last updated on Dec 29, 2024.

Note: This document provides detailed information about Plenvu.

Applies to polyethylene glycol 3350 with electrolytes: oral powder for solution Side Effects associated with polyethylene glycol 3350 with electrolytes. Some dosage forms listed on this page may not apply specifically to the brand name Plenvu.

Applies to polyethylene glycol 3350 with electrolytes: oral powder for solution.

Precautions

It is important that your doctor check your progress closely for any problems that may be caused by this medicine. Blood and urine tests may be needed to check for unwanted effects.

Do not use this medicine together with other laxatives (eg, bisacodyl [Dulcolax®] or sodium picosulfate [Dulcolax® Pico, CitraFleet®]).

Contact your doctor right away if you have decreased urination, dizziness, headache, or vomiting. These could be symptoms of a loss of too much body fluid (dehydration).

Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Make sure your doctor knows if you had a heart rhythm problem, including QT prolongation.

This medicine may increase your risk for seizures. This is more likely to occur if you take medicine for depression, if you are withdrawing from alcohol or benzodiazepine use, or if you have low sodium level in the blood (hyponatremia). Talk to your doctor if you have any concerns.

If you have severe bloating or stomach discomfort after you take the first dose, you may need to wait until your symptoms improve before you take the second dose or you can take smaller sips of the mixture.

Keep yourself hydrated before, during, and after using this medicine. Drink extra fluids so you will pass more urine. This may help prevent kidney problems. Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem.

This medicine may cause serious bowel problems (eg, colon ulcers, ischemic colitis). Check with your doctor right away if you have stomach pain and tenderness, bloody stools, or rectal bleeding.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing or swallowing, or large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals after using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Plenvu

Along with its needed effects, polyethylene glycol 3350 with electrolytes (the active ingredient contained in Plenvu) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking polyethylene glycol 3350 with electrolytes:

More common side effects

  • full or bloated feeling
  • pain in the upper stomach
  • pressure in the stomach
  • stomach pain
  • swelling of the stomach area
  • vomiting

Rare side effects

  • confusion
  • decreased urine output
  • dizziness
  • dry mouth
  • fast or irregular heartbeat
  • headache
  • increased thirst
  • loss of appetite
  • loss of consciousness
  • muscle pain or cramps
  • numbness or tingling in the hands, feet, fingertips, lips, or mouth
  • seizures
  • swelling of the face, ankles, or hands
  • unusual tiredness or weakness

Incidence not known

  • blistering, crusting, irritation, itching, or reddening of the skin
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or black, tarry stools
  • bloody urine
  • blue lips and fingernails
  • blurred vision
  • chest pain or tightness
  • chills
  • constipation
  • cough
  • coughing that sometimes produces a pink frothy sputum
  • cracked, dry, scaly skin
  • difficult, fast, noisy breathing
  • difficulty swallowing
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • heartburn
  • hives, itching, skin rash
  • increase in heart rate
  • increased sweating
  • lightheadedness
  • lower back or side pain
  • nausea
  • nervousness
  • pale skin
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid breathing
  • rapid weight gain
  • runny nose
  • severe stomach pain
  • slow heartbeat
  • sunken eyes
  • swelling of the neck
  • thirst
  • throat tightness
  • tingling of the hands or feet
  • tremor
  • trouble breathing
  • unusual weight gain or loss
  • vomiting of blood or material that looks like coffee grounds
  • wrinkled skin

Other side effects of Plenvu

Some side effects of polyethylene glycol 3350 with electrolytes may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • burning, itching, or pain around the anus
  • difficulty with sleeping
  • feeling unusually cold
  • general feeling of discomfort or illness
  • hunger
  • shivering

Less common side effects

  • belching
  • indigestion
  • stomach discomfort or upset

For healthcare professionals

Applies to polyethylene glycol 3350 with electrolytes: oral kit, oral powder for reconstitution.

General adverse events

The most common adverse events were abdominal distension, anal discomfort, thirst, nausea, and abdominal pain. Since diarrhea is considered part of the efficacy of this product, it was not defined as an adverse reaction.[Ref]

Gastrointestinal

Metabolic

Other

Nervous system

Psychiatric

Hypersensitivity

Cardiovascular

Dermatologic

Respiratory

See also:

References

1. "Product Information. Golytely (polyethylene glycol 3350 with electrolytes)." Braintree

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

4. (2016) "Product Information. MoviPrep (polyethylene glycol 3350 with electrolytes)." Physicians Total Care

5. (2016) "Product Information. TriLyte with Flavor Packs (polyethylene glycol 3350 with electrolytes)." Alaven Pharmaceuticals

6. (2016) "Product Information. Colyte with Flavor Packs (polyethylene glycol 3350 with electrolytes)." Alaven Pharmaceuticals

Frequently asked questions

Further information

Plenvu side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.