Pedia-Lax Enema Side Effects

Generic name: sodium biphosphate / sodium phosphate

Medically reviewed by Drugs.com. Last updated on Aug 6, 2023.

Note: This document contains side effect information about sodium biphosphate / sodium phosphate. Some dosage forms listed on this page may not apply to the brand name Pedia-Lax Enema.

Applies to sodium biphosphate / sodium phosphate: oral solution, oral tablet. Other dosage forms:

• intravenous solution
• rectal enema

Serious side effects of Pedia-Lax Enema

Along with its needed effects, sodium biphosphate / sodium phosphate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sodium biphosphate / sodium phosphate:

More common

• Bloating
• stomach pain

Incidence not known

• Agitation
• bloody or cloudy urine
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• confusion
• cough
• decrease in the frequency or amount of urine
• decreased awareness or responsiveness
• depression
• difficult or labored breathing
• difficult or painful urination
• difficulty with swallowing
• dizziness
• fainting
• fast, slow, or irregular heartbeat
• headache
• hives, itching, skin rash
• hostility
• increased blood pressure
• increased thirst
• irritability
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
• loss of appetite
• loss of consciousness
• lower back or side pain
• muscle twitching
• nausea
• noisy breathing
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• rapid weight gain
• redness of the skin
• seizures
• severe sleepiness
• sudden decrease in the amount of urine
• swelling of the face, ankles, or hands
• tightness in the chest
• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
• vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking sodium biphosphate / sodium phosphate:

Symptoms of overdose

• Blurred vision
• chest pain or discomfort
• decreased frequency of urine
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• dry mouth
• increase in heart rate
• increased thirst
• lightheadedness
• loss of appetite
• lower back or side pain
• muscle cramps in the hands, arms, feet, legs, or face
• muscle pain
• pounding or rapid pulse
• rapid breathing
• restlessness
• stomach cramps
• sunken eyes
• sweating
• tremor
• weakness
• weight gain
• wrinkled skin

For Healthcare Professionals

Applies to sodium biphosphate / sodium phosphate: oral solution, oral tablet, rectal enema.

General

The most common adverse events were abdominal bloating, nausea, abdominal pain, and vomiting.^[Ref]

Gastrointestinal

Very common (10% or more): Bloating (39%), nausea (37%), abdominal pain (24%), vomiting (10%)^[Ref]

Renal

Postmarketing reports: Renal impairment, increased blood urea nitrogen (BUN), increased creatinine, acute renal failure, acute phosphate nephropathy, nephrocalcinosis, renal tubular necrosis^[Ref]

Nervous system

Postmarketing reports: Seizures^[Ref]

Cardiovascular

Postmarketing reports: Arrhythmias^[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity reactions (including anaphylaxis, rash, pruritus, urticaria, throat tightness, bronchospasm, dyspnea, pharyngeal edema, dysphagia, paresthesia, swelling of the lips and tongue, and facial swelling)^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer