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Patiromer Side Effects

Medically reviewed by Last updated on Oct 26, 2020.

For the Consumer

Applies to patiromer: oral powder for suspension

Side effects requiring immediate medical attention

Along with its needed effects, patiromer may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking patiromer:

More common

  • Drowsiness
  • loss of appetite
  • mood or mental changes
  • muscle spasms (tetany) or twitching
  • nausea
  • seizures
  • trembling
  • unusual tiredness or weakness
  • vomiting

Side effects not requiring immediate medical attention

Some side effects of patiromer may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Difficulty having a bowel movement

Less common

  • Bloated or full feeling
  • diarrhea
  • excess air or gas in the stomach or bowels
  • passing gas
  • stomach discomfort

For Healthcare Professionals

Applies to patiromer: oral powder for reconstitution


Common (1% to 10%): Constipation, diarrhea, nausea, abdominal discomfort, flatulence

Uncommon (0.1% to 1%): Vomiting[Ref]


Uncommon (0.1% to 1%): Edema of the lips[Ref]


Common (1% to 10%): Hypomagnesemia, hypokalemia[Ref]


Common (1% to 10%): Approximately 4.7% of patients in clinical trials developed hypokalemia with a serum potassium value less than 3.5 mEq/L. Approximately 9% of patients in clinical trials developed hypomagnesemia with a serum magnesium value less than 1.4 mg/dL.[Ref]


1. "Product Information. Veltassa (patiromer)." Relypsa, Inc., Redwood City, CA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.